307353-87-3

Basic information

• Product Name: C₂₂H₁₆N₄O₄S
• Synonyms: C₂₂H₁₆N₄O₄S
• CAS NO: 307353-87-3
• Molecular Weight: 432.459
• Mol File: 307353-87-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₁₆N₄O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₁₆N₄O₄S(307353-87-3)
• EPA Substance Registry System: C₂₂H₁₆N₄O₄S(307353-87-3)

Safety Data

• Hazardous Substances Data: 307353-87-3(Hazardous Substances Data)

Upstream product

• 105350-49-0 C₉H₈N₂OS 

Downstream Products

• 307353-88-4 C₂₁H₁₄N₄O₄S 

Relevant articles and documents

Derivatives of quinoline as inhibitors for MEK

1. A compound of formula (I) or a pharmaceutically acceptable salt thereof. wherein: n is 0-1; X and Y are independently selected from -NH-, -O-, -S-, or -NR8- where R8 is alkyl of 1-6 carbon atoms and X may additionally comprise a CH2 group; R7 is a group (CH2)mR9 where m is 0,or an integer of from 1-3 and R9 is a substituted aryl group, an optionally substituted cycloalkyl ring of up to 10 carbon atoms, or an optionally substituted heterocyclic ring or an N-oxide of any nitrogen containing ring; R6 is a divalent cycloalkyl of 3 to 7 carbon atoms, which may be optionally further substituted with one or more alkyl of 1 to 6 carbon atom groups; or is a divalent pyridinyl, pyimidinyl, or phenyl ring; wherein the pyridinyl, pyrimidinyl, or phenyl ring may be optionally further substituted with one or more specified groups; R1, R2, R3 and R4 are each independently selected from hydrogen or various specified organic groups. Compounds are useful as pharmaceuticals for the inhibition of MEK activity.