307519-45-5Relevant articles and documents
Synthesis and receptor binding properties of 2β-alkynyl and 2β-(1,2,3-triazol)substituted 3β-(substituted phenyl)tropane derivatives
Jin, Chunyang,Navarro, Hernan A.,Carroll, F. Ivy
, p. 5529 - 5535 (2008/12/20)
A series of 2β-alkynyl and 2β-(1,2,3-triazol)substituted 3β-(substituted phenyl)tropanes were synthesized and evaluated for affinities at dopamine, serotonin, and norepinephrine membrane transporters using competitive radioligand binding assays. All teste
Synthesis and biological evaluation of 2-substituted 3β-tolyltropane derivatives at dopamine, serotonin, and norepinephrine transporters
Xu, Lifen,Izenwasser, Sari,Katz, Jonathan L.,Kopajtic, Theresa,Klein-Stevens, Cheryl,Zhu, Naiju,Lomenzo, Stacey A.,Winfield, Leyte,Trudell, Mark L.
, p. 1203 - 1210 (2007/10/03)
A series of eight 2-substituted 3-tolyltropane derivatives were synthesized, and the in vitro and in vivo biological activities as dopamine uptake inhibitors were determined. From the in vitro structure-activity data, it is apparent that a tolyl group in
