307521-00-2

Basic information

• Product Name: 2-(3,4-bis(benzyloxy)phenyl)-3-hydroxy-4H-chroMen-4-one
• Synonyms: 2-(3,4-bis(benzyloxy)phenyl)-3-hydroxy-4H-chroMen-4-one;2-(3,4-BIS(BENZYLOXY)PHENYL)-3-HYDROXY-4H-CHROMEN-4-ONE（WS201317）
• CAS NO: 307521-00-2
• Molecular Formula: C₂₉H₂₂O₅
• Molecular Weight: 450.48198
• Mol File: 307521-00-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3,4-bis(benzyloxy)phenyl)-3-hydroxy-4H-chroMen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-bis(benzyloxy)phenyl)-3-hydroxy-4H-chroMen-4-one(307521-00-2)
• EPA Substance Registry System: 2-(3,4-bis(benzyloxy)phenyl)-3-hydroxy-4H-chroMen-4-one(307521-00-2)

Safety Data

• Hazardous Substances Data: 307521-00-2(Hazardous Substances Data)

Usage

Core structure

3-hydroxy-4H-chromen-4one, a flavonoid known for antioxidant and anti-inflammatory properties.

Substitution

Two benzyl ether groups attached to the phenyl ring, potentially enhancing bioavailability and therapeutic effects.

Potential pharmaceutical uses

Anti-cancer, anti-diabetic, and anti-inflammatory activities.

Upstream product

• 808741-39-1 (E)-3-(3,4-Bis-benzyloxy-phenyl)-1-(2-hydroxy-phenyl)-propenone 
• 118-93-4 o-hydroxyacetophenone 
• 5447-02-9 3,4-dibenzyloxybenzaldehyde 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 1148010-41-6 (E)-3-(3',4'-bis(benzyloxy)phenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one 
• 99-50-3 3,4-Dihydroxybenzoic acid 
• 2150-43-8 3,4-dihydroxybenzoic acid methyl ester 
• 54544-05-7 3,4-bis-benzyloxybenzoic acid methyl ester 

Downstream Products

• 331651-16-2 3',4'-dibenzyloxy-3-tetraacetylglucosylflavone 
• 331651-08-2 3-(8-bromooctyloxy)-3',4'-dibenzyloxyflavone 
• 331651-05-9 3-(6-chlorohexyloxy)-3',4'-dibenzyloxyflavone 
• 307521-42-2 ethyl (3',4'-dibenzyloxyflavon-3-yl)oxyacetate 
• 307521-38-6 3-(3-chloropropoxy)-3',4'-dibenzyloxyflavone 
• 307521-36-4 3-(3-bromopropoxy)-3',4'-dibenzyloxyflavone 
• 307521-27-3 3',4'-dibenzyloxy-3-hexaacetylrutinosylflavone 
• 918309-45-2 acetic acid 4,5-diacetoxy-6-acetoxymethyl-2-[2-(3,4-bis-benzyloxy-phenyl)-4-oxo-4H-chromen-3-yloxy]-tetrahydro-pyran-3-yl ester 
• 307521-67-1 2-(3',4'-dihydroxyphenyl)-3-β-D-galactosyl-4H-chromen-4-one 
• 918309-46-3 acetic acid 4,5-diacetoxy-6-acetoxymethyl-2-[2-(3,4-dihydroxy-phenyl)-4-oxo-4H-chromen-3-yloxy]-tetrahydro-pyran-3-yl ester 
• 307521-53-5 3',4'-dihydroxy-3-methoxyflavone 
• 307521-15-9 (3',4'-dibenzyloxyflavon-3-yl)oxyacetic acid 
• 307521-17-1 3',4'-dibenzyloxy-3-(3-dimethylaminopropoxy)flavone 
• 307521-67-1 3',4'-dihydroxy-3-glucosylflavone 

Relevant articles and documents

NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS

The present invention provides novel analogues of epicatechin and related polyphenols, their variously functionalized derivatives, process for preparation of the same, composition comprising these compounds and their method of use.

Novel flavonoids

Novel flavonoids of formula (I) 1where A and E form together a C—C or C=C bond; R1, R2, R3, and R4 are H, OH, O(CH2)n— aromatic group, n=0-8; O(CH2)n N(CH3)q with n=0-8, q=0-3; O(CH2)n OH with n=1-8; O(CH2)n-halide with n=1-8; O(CH2)n COOH with n=0-8; O(CH2)n COOR′ with n=0-8 and R′ is C1-C8 alkyl or an aromatic group; O(CH2)n CONH R″ with n=0-8 and R″ is C1-C8 alkyl or an aromatic group, and sugars in mono-, di- or trimeric form or analogues thereof, with the proviso that R1 is not H, at least two of R2, R3 and R4 are H, and at most one of R1, R2, R3 and R4 is OH, are useful for the treatment of drug-induced toxicity, doxorubicin-induced cardiotoxicity, free radical mediated diseases, lung diseases, cancer, diabetes mellitus, cardiovascular disease, or arteriosclerosis.