30826-85-8

Basic information

• Product Name: 1,3-Diethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one
• Synonyms: 1,3-Diethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one
• CAS NO: 30826-85-8
• Molecular Formula: C8H16 N2 O
• Molecular Weight: 156.23
• Mol File: 30826-85-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 248.3°C at 760 mmHg
• Flash Point: 98.8°C
• Appearance: /
• Density: 0.975g/cm³
• Vapor Pressure: 0.0245mmHg at 25°C
• Refractive Index: 1.465
• CAS DataBase Reference: 1,3-Diethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Diethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one(30826-85-8)
• EPA Substance Registry System: 1,3-Diethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one(30826-85-8)

Safety Data

• Hazardous Substances Data: 30826-85-8(Hazardous Substances Data)

Usage

Type of Compound

Heterocyclic compound

Primary Use

Antihypertensive agent

Mechanism of Action

Calcium channel blocker

Function

Relaxes blood vessels and reduces high blood pressure

Potential Applications

Treatment of cardiovascular diseases (angina, arrhythmias)

Additional Properties

Analgesic and anti-inflammatory agent (preclinical studies)

Research Status

Further research needed to understand mechanism of action and therapeutic uses

Pharmaceutical Industry

Promising medicinal properties and potential value

InChI:InChI=1/C8H16N2O/c1-3-9-6-5-7-10(4-2)8(9)11/h3-7H2,1-2H3

Upstream product

• 1852-17-1 3,4,5,6-tetrahydropyrimidin-2(1H)-one 
• 75-03-6 ethyl iodide 
• 2055-46-1 3,4,5,6-tetrahydropyrimidine-2-thione 
• 6497-86-5 2-ethylsulfanyl-1,4,5,6-tetrahydro-pyrimidine 
• 10061-68-4 N,N'-diethyl-1,3-propanediamine 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Novel synthesis of N, n′-dialkyl cyclic ureas using sulfur-assisted carbonylation and oxidation

The first example of cyclic urea synthesis from secondary amines by the use of sulfur-assisted carbonylation and oxidation was established. By combined sulfur-assisted carbonylation of secondary a, ay diamines under an ambient pressure of carbon monoxide

Intermolecular hydroamination of ethylene and 1-alkenes with cyclic ureas catalyzed by achiral and chiral gold(I) complexes

-

Reduction of Cyclic Ureas with Lithium Aluminum Hydride

A series of 1,3-dialkyl-2-imidazolidinones 1 and 1,3-dialklyltetrahydro -2(1H)-pyrimidinones 2 were reduced to the corresponding aminals 3 and 4, respectively, when treated with excess lithium aluminum hydride in ether.The rate of reduction is affected dr