3084-48-8

Basic information

• Product Name: trihexylphosphine oxide
• Synonyms: trihexylphosphine oxide;trihexyl-phosphine oxid;Ai3-51003;Brn 1782166;Einecs 221-392-1;Nsc 41936;Phosphine oxide, trihexyl-
• CAS NO: 3084-48-8
• Molecular Formula: C₁₈H₃₉OP
• Molecular Weight: 302.475421
• EINECS: 221-392-1
• Product Categories: Phosphine Oxides and Sulfides
• Mol File: 3084-48-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 34-35 °C
• Boiling Point: 163°C
• Flash Point: 212.9°C
• Appearance: /
• Density: 0.864g/cm³
• Vapor Pressure: 3.79E-07mmHg at 25°C
• Refractive Index: 1.44
• CAS DataBase Reference: trihexylphosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: trihexylphosphine oxide(3084-48-8)
• EPA Substance Registry System: trihexylphosphine oxide(3084-48-8)

Safety Data

• Hazardous Substances Data: 3084-48-8(Hazardous Substances Data)

Usage

General Description

Trihexylphosphine oxide is a phosphine oxide compound with the chemical formula C18H39OP. It is a clear to slightly yellow liquid with a slightly floral odor and is insoluble in water, but soluble in organic solvents. Trihexylphosphine oxide is primarily used as a solvent extraction agent in separations involving transition metals, such as the extraction of nickel and copper from aqueous sulfate solutions. It is also used as a phase transfer catalyst in organic synthesis reactions. Additionally, trihexylphosphine oxide is used as an additive in some formulations to improve the thermal and oxidative stability of polymers and lubricants. It is considered to have low acute toxicity, but precaution should be taken when handling it due to its potential for skin and eye irritation.

InChI:InChI=1/C18H39OP/c1-4-7-10-13-16-20(19,17-14-11-8-5-2)18-15-12-9-6-3/h4-18H2,1-3H3

Upstream product

• 4168-73-4 trihexylphosphine 
• 638-45-9 1-Iodohexane 
• 3761-92-0 n-hexylmagnesium bromide 
• 258864-54-9 trihexyl(tetradecyl)phosphonium chloride 
• 111-25-1 1-bromo-hexane 

Downstream Products

• 4168-73-4 trihexylphosphine 

Relevant articles and documents

The influence of the sacrificial anode nature on the mechanism of electrochemical arylation and alkylation of white phosphorus

The material of the sacrificial anode has a substantial effect on the nature and yield of the target products of electrochemical phosphorylation of organic halides by white phosphorus in the presence of the nickel complexes with 2,2′-bipyridine. The use of the zinc anode results in the products with tricoordinated phosphorus, viz., triorganylphosphines, the reaction on the aluminum anode affords triorganylphosphine oxides, and the presence of Mg 2+ ions in the reaction mixture provides the transformation of white phosphorus into cyclic phosphines (PhP)5.

The Michaelis-Becker reaction in phosphonium and imidazolium ionic liquids

The Michaelis-Becker reaction was performed in imidazolium ionic liquids using sodium hydroxide as base or sodium dialkylphosphites with good yield and selectivities. The analogous reaction performed in phosphonium ionic liquids resulted in decomposition to phosphine oxides. Copyright

Peroxo-containing metal complexes having amine oxide, phosphine oxide, arsine oxide, pyridine N-oxide or pyridine ligands as epoxidation catalysts

PCT No. PCT/EP96/03888 Sec. 371 Date Mar. 11, 1998 Sec. 102(e) Date Mar. 11, 1998 PCT Filed Sep. 4, 1996 PCT Pub. No. WO97/10054 PCT Pub. Date Mar. 20, 1997Olefins can be epoxidized using catalysts I where M is a metal of the 4th to 7th transition group of the Periodic Table of the Elements, L1 is an amine oxide, phosphine oxide, arsine oxide, pyridine N-oxide or pyridine ligand of the formula II, III, VII or VIII, L2 is a customary auxiliary ligand or a further ligand L1 or a free coordination site, X is oxo oxygen or an imido ligand, m is 1 or 2, and n is 1, 2 or 3.