30885-29-1

Basic information

• Product Name: 3-(4-Chlorophenyl)pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide
• Synonyms: 3-(4-Chlorophenyl)pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide
• CAS NO: 30885-29-1
• Molecular Weight: 296.716
• Mol File: 30885-29-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-Chlorophenyl)pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Chlorophenyl)pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide(30885-29-1)
• EPA Substance Registry System: 3-(4-Chlorophenyl)pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide(30885-29-1)

Safety Data

• Hazardous Substances Data: 30885-29-1(Hazardous Substances Data)

Upstream product

• 62538-21-0 2-(4-chloro-phenyl)-3-oxo-propionitrile 
• 3034-19-3 (2-nitrophenyl)hydrazine 
• 30885-23-5 1-(2-Nitrophenyl)-4-(4-chlorophenyl)-5-aminopyrazole 

Relevant articles and documents

Benzodiazepine receptor ligands III. Synthesis and biological evaluation of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides

A new series of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides and their 8-chloro derivatives were synthesized, and their benzodiazepine receptor (BZR) affinities were evaluated in vitro in comparison to lead compound 3-ethoxycarbonyl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide (29) [1,2]. None of the new compounds showed significant affinity for BZR. On the basis of a pharmacophore/receptor model suggested for lead compound 29, some hypotheses to explain the inactivity of new derivatives are discussed.