309254-39-5Relevant articles and documents
Biaryl synthesis via direct arylation: Establishment of an efficient catalyst for intramolecular processes
Campeau, Louis-Charles,Parisien, Mathieu,Leblanc, Melissa,Fagnou, Keith
, p. 9186 - 9187 (2004)
In this Communication, we describe direct arylation reactions with improved scope and catalyst activity for the intramolecular formation of biaryl compounds. This was achieved through the establishment of a highly active and robust catalyst system and the subsequent development of a novel phosphine ligand 27. The enhanced catalytic activity extends these transformations to include previously unreactive and poorly reactive substrates, and allows for very low catalyst loadings to be employedas little as 0.1 mol %. Copyright
Impregnated palladium on magnetite as catalyst for direct arylation of heterocycles
Cano, Rafael,Pérez, Juana M.,Ramón, Diego J.,McGlacken, Gerard P.
, p. 1043 - 1050 (2016/07/06)
Palladium impregnated on magnetite is an efficient, cheap and easy to prepare catalyst for the direct arylation of heterocycles. Good yields are afforded under relatively mild conditions and a broad substrate scope is evident. The catalyst is regioselective in many cases, affording arylated products, at the C2- or C3-position (depending of the heterocycle used). The methodology can be extended to prepare chromenes through an intramolecular direct arylation reaction. Some evidence is provided for two catalyst deactivation pathways, which prevents efficient recycling.
Neocuproine-KOtBu promoted intramolecular cross coupling to approach fused rings
Sun, Chang-Liang,Gu, Yi-Fan,Huang, Wei-Ping,Shi, Zhang-Jie
supporting information; experimental part, p. 9813 - 9815 (2011/10/11)
Polycycles can be produced with different linkages (A, B = O, N, C, S) by constructing biaryl C-C bonds via neocuproine-KOtBu promoted cross coupling between C-Xs and C-Hs.
