309962-67-2

Basic information

• Product Name: (R)-3-N-Boc-3-(methylamino)piperidine
• Synonyms: (R)-3-N-Boc-3-(methylamino)piperidine;(R)-TERT-BUTYLMETHYL(PIPERIDIN-3-YL)CARBAMATE;(R)-3-Boc-3-(Methylamino)piperidine;(R)-tert-butyl piperidin-3-ylMethylcarbaMate;Methyl(3R)-3-piperidinylcarbamic acid tert-butyl ester;(R)-3-(N-Boc-MethylaMino)piperidine;tert-butyl (R)-methyl(piperidin-3-yl)carbamate;tert-butyl N-methyl-N-[(3R)-piperidin-3-yl]carbamate
• CAS NO: 309962-67-2
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.31
• Mol File: 309962-67-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 288℃
• Flash Point: 128℃
• Appearance: /
• Density: 1.01
• Vapor Pressure: 0.00242mmHg at 25°C
• Refractive Index: 1.485
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (R)-3-N-Boc-3-(methylamino)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-N-Boc-3-(methylamino)piperidine(309962-67-2)
• EPA Substance Registry System: (R)-3-N-Boc-3-(methylamino)piperidine(309962-67-2)

Safety Data

• Hazardous Substances Data: 309962-67-2(Hazardous Substances Data)

Usage

General Description

(R)-3-N-Boc-3-(methylamino)piperidine is a chemical compound that belongs to the class of piperidine derivatives. It is characterized by the presence of a tertiary amine group and a Boc (tert-butoxycarbonyl) protective group on the nitrogen atom. The molecule possesses a chiral center, and the (R)-stereoisomer refers to the configuration of the molecule. (R)-3-N-Boc-3-(methylamino)piperidine has potential applications in organic synthesis, particularly in the preparation of pharmaceutical intermediates and ligands for asymmetric catalysis. The Boc protective group provides stability to the amine functionality, making it a valuable building block for the synthesis of various nitrogen-containing compounds. Additionally, the presence of the methylamino group adds functionality and versatility to the molecule, making it useful in a range of chemical transformations.

InChI:InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13(4)9-6-5-7-12-8-9/h9,12H,5-8H2,1-4H3/t9-/m1/s1

Upstream product

• 1124199-23-0 (R)-benzyl 3-(tert-butoxycarbonyl(methyl)amino)piperidine-1-carboxylate 
• 309956-78-3 (R)-piperidin-3-ylcarbamic acid tert-butyl ester 
• 485820-12-0 (R)-3-(tert-butoxycarbonylamino)piperidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

PYRROLOPYRIDINES AS KINASE INHIBITORS

Compounds of Formula (I) are useful for inhibition of CHKl and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Heterocyclic substituted aminoazacycles useful as central nervous system agents

Heterocyclic substituted aminoazacyclic compounds of the formula (I):Z-R3, wherein Z is a defined aminoazacycle and R3 is a defined heterocycle moiety, pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.