31025-12-4Relevant articles and documents
Bromelain catalyzed synthesis of peptides in organic solvent
Tai, Dar-Fu,Fu, Shu-Lin
, p. 179 - 183 (2007/10/03)
For the first time, immobilized bromelain was shown to maintain high catalytic activity in organic solvent and to form peptide bonds. It requires only 7 hours to obtain Cbz-Gly-L-Leu-OMe in 85% yield. The precursor of aspartame (Cbz-L-Asp-L-Phe-OMe) and other dipeptides were also synthesized by this method.
The structure of viscosin, a peptide antibiotic. II. Syntheses of D- and L-3-hydroxyacylhexapeptides including the proposed structure of viscosin and its optical isomers.
Hiramoto,Okada,Nagai
, p. 1315 - 1320 (2007/10/13)
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