311343-03-0Relevant articles and documents
Synthesis and Biological Evaluation in Human Monocyte-Derived Macrophages of N-(N-Acetyl-L-cysteinyl)-S-acetylcysteamine Analogues with Potent Antioxidant and Anti-HIV Activities
Oiry, Jo?l,Mialocq, Patricia,Puy, Jean-Yves,Fretier, Philippe,Dereuddre-Bosquet, Nathalie,Dormont, Dominique,Imbach, Jean-Louis,Clayette, Pascal
, p. 1789 - 1795 (2004)
We synthesized a series of N-(N-acetyl-L-cysteinyl)-S-acetylcysteamine (10) analogues bearing various acyl groups on thiol cysteine or cysteamine residues, to investigate the structure-activity relationship for pro-GSH and anti-HIV properties in human mac
Novel antioxidants, preparation processes and their uses
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Page 17-18, (2010/02/08)
The invention concerns a process for preparing compounds of general formula (I) wherein R and R′ represent an alkyl radical or an aryl group; and R″ is hydrogen or a CO—R1 group wherein R1 is an alkyl radical or an aryl group; and wherein these compounds are or not in the thiazolidine form; by protecting the N-acyl-L-cysteine to form an intermediate compound; and then by coupling said intermediate compound with S-acylcysteamine hydrochloride or with thiazolidine.
