311464-46-7Relevant articles and documents
Novel erythromycin A derivatives: Synthesis of 11,12-benzoxazine ketolides
Zhu, Bin,Maden, Amy,Macielag, Mark J.
, p. 1783 - 1785 (2007/10/03)
A novel series of 11,12-benzoxazine ketolide derivatives of erythromycin A has been synthesized. The C11,C12-benzoxazine structure was constructed stereoselectively through an intramolecular Michael addition of a C12-O-(2-aminophenyl) group to the enone functionality of the 10,11-anhydro erythromycin A derivative 3.