311823-24-2Relevant articles and documents
Synthesis of conformationally constrained 5,6,7,8-tetrahydroimidazo[1,5-a]pyridine inhibitors of Farnesyltransferase
Dinsmore, Christopher J.,Zartman, C. Blair,Baginsky, Walter F.,O'Neill, Timothy J.,Koblan, Kenneth S.,Chen, I-Wu,McLoughlin, Debra A.,Olah, Timothy V.,Huff, Joel R.
, p. 3473 - 3476 (2007/10/03)
(Equation Presented) Synthesis of the 8-amino-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine ring system was accomplished by intramolecular cyclization of an iminium ion, derived from condensation of an amine and a substituted γ-(1-imidazolyl)butyraldehyde. The