31206-25-4Relevant articles and documents
Synthesis of sulfonimide-based dendrimers and dendrons possessing mixed 1?→?2 and 1?→?4 branching motifs
Kolotylo, Mykola,Holovatiuk, Volodymyr,Bondareva, Julia,Lukin, Oleg,Rozhkov, Vladimir
, p. 352 - 354 (2019)
The synthesis of dendrimers and a chlorosulfo-dendron possessing a unique combination of 1 → 2 and 1 → 4 branching types is described. The procedure consists of a two-step preparation of 3,5-dinitrobenzene-1-sulfonyl chloride, which was used for the persu
AROMATIC SULFONAMIDE DERIVATIVES AND THEIR USE AS ANATAGON I STS OR NEGATIVE ALLOSTERIC MODULATORS OF P2X4
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Page/Page column 74, (2018/06/30)
Substituted aromatic sulfonamides of formula (I), pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease.
CHEMICAL COMPOUNDS
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Page/Page column 170-171, (2013/07/05)
The invention is directed to substituted quinoline derivatives. Specifically, the invention is directed to compounds according to Formula I: wherein R, R1, R2, R3 and R4 are defined herein. The compounds of the invention are inhibitors of lactate dehydrogenase A and can be useful in the treatment of cancer and diseases associated with tumor cell metabolism, such as cancer, and more specifically cancers of the breast, colon, prostate and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting lactate dehydrogenase A activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.