31217-97-7

Basic information

• Product Name: N,N'-(4-bromo-1,2-phenylene)diacetamide
• Synonyms: N,N'-(4-bromo-1,2-phenylene)diacetamide
• CAS NO: 31217-97-7
• Molecular Weight: 271.114
• Mol File: 31217-97-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N'-(4-bromo-1,2-phenylene)diacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-(4-bromo-1,2-phenylene)diacetamide(31217-97-7)
• EPA Substance Registry System: N,N'-(4-bromo-1,2-phenylene)diacetamide(31217-97-7)

Safety Data

• Hazardous Substances Data: 31217-97-7(Hazardous Substances Data)

Upstream product

• 75-36-5 acetyl chloride 
• 1575-37-7 4-Bromo-benzene-1,2-diamine 
• 108-24-7 acetic anhydride 
• 881-50-5 N-(4-bromo-2-nitrophenyl)acetamide 

Downstream Products

• 2072-30-2 2-acetamido-5-bromo-1,4-benzoquinone 
• 78680-92-9 2-methylbenzoxazole 

Relevant articles and documents

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TREATMENT OF CANCERS HAVING K-RAS MUTATIONS

The present invention provides a method of treating a cancer associated with a K-ras mutation in a subject in need thereof. The method comprises the steps of: (1) identifying a subject with a cancer associated with a K-ras mutation; and (2) administering to the subject (i) an inhibitor of PI3 kinase and (ii) an HDAC inhibitor, wherein the PI3 kinase inhibitor and the HDAC inhibitor are administered in amounts which together are therapeutically effective.

BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR

The present invention provides a novel benzene derivative or thiophene derivative useful as a VAP-1 inhibitor, or a medicament for the prophylaxis or treatment of a VAP-1 associated disease and the like, namely, a compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof.