3131-84-8 Usage
Description
Glutaryl-coenzyme A, also known as glutaryl-CoA, is a compound formed by the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of glutaric acid. It is an omega-carboxyacyl-CoA and plays a crucial role in various biochemical processes.
Uses
Used in Pharmaceutical Industry:
Glutaryl-coenzyme A is used as an intermediate in the metabolism of certain amino acids, such as lysine, tryptophan, and hydroxylysine. It is involved in the breakdown of these amino acids through the corresponding catabolic pathways, which are essential for the proper functioning of the human body.
Used in Biochemical Research:
Glutaryl-coenzyme A is used as a research tool in the field of biochemistry to study the mechanisms of various metabolic pathways and enzyme functions. It helps researchers understand the role of coenzyme A and its interactions with different substrates.
Used in Enzyme Assays:
Glutaryl-coenzyme A is used as a substrate in enzyme assays to measure the activity of specific enzymes involved in the metabolism of glutaric acid. This helps in the diagnosis of certain genetic disorders and the evaluation of enzyme deficiencies.
Used in Drug Development:
Glutaryl-coenzyme A may be used in the development of new drugs targeting metabolic pathways related to glutaric acid metabolism. By modulating the activity of enzymes involved in these pathways, it could potentially lead to the development of therapeutic agents for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 3131-84-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,3 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3131-84:
(6*3)+(5*1)+(4*3)+(3*1)+(2*8)+(1*4)=58
58 % 10 = 8
So 3131-84-8 is a valid CAS Registry Number.
3131-84-8Relevant articles and documents
Identification of an α-Oxoamine Synthase and a One-Pot Two-Step Enzymatic Synthesis of α-Amino Ketones
Zhou, Ting,Gao, Du,Li, Jia-Xin,Xu, Min-Juan,Xu, Jun
supporting information, p. 37 - 41 (2020/12/21)
Alb29, an α-oxoamine synthase involved in albogrisin biosynthesis in Streptomyces albogriseolus MGR072, was characterized and responsible for the incorporation of l-glutamate to acyl-coenzyme A substrates. Combined with Alb29 and Mgr36 (an acyl-coenzyme A ligase), a one-pot enzymatic system was established to synthesize seven α-amino ketones. When these α-amino ketones were fed into the alb29 knockout strain Δalb29, respectively, the albogrisin analogs with different side chains were observed.
