313229-90-2 Usage
Description
1,4,8,11-Tetraazabicyclo[6.6.2]hexadecane-4,11-diacetic acid, also known as CB-TE 2A, is a chemical compound with a unique structure that consists of a tetraazabicyclohexadecane core with diacetic acid functional groups. This molecule is characterized by its ability to form stable complexes with various metal ions, particularly copper, and has been found to have potential applications in the field of medical imaging and diagnostics.
Uses
Used in Medical Imaging:
1,4,8,11-Tetraazabicyclo[6.6.2]hexadecane-4,11-diacetic acid is used as a chelating agent for the preparation of 64Cu-CBTE2A-galectin-3 peptide as a PET (Positron Emission Tomography) radiotracer for breast carcinoma. The application reason is that this compound can effectively bind to copper-64, a radioisotope with suitable decay properties for PET imaging, and form a stable complex with the target peptide, allowing for the detection and monitoring of breast cancer in patients.
Check Digit Verification of cas no
The CAS Registry Mumber 313229-90-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,3,2,2 and 9 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 313229-90:
(8*3)+(7*1)+(6*3)+(5*2)+(4*2)+(3*9)+(2*9)+(1*0)=112
112 % 10 = 2
So 313229-90-2 is a valid CAS Registry Number.
313229-90-2Relevant articles and documents
Synthesis and characterization of cross-bridged cyclams and pendant-armed derivatives and structural studies of their copper(II) complexes
Wong, Edward H.,Weisman, Gary R.,Hill, Daniel C.,Reed, David P.,Rogers, Mark E.,Condon, Jeffrey S.,Fagan, Maureen A.,Calabrese, Joseph C.,Lam, Kin-Chung,Guzei, Ilia A.,Rheingold, Arnold L.
, p. 10561 - 10572 (2000)
A series of 1,4,8,11-tetraazabicyclo[6.6.2]hexadecane ligands, including the parent compound, N,N′-dialkyl variants, and the first N,N′-di-pendant-arm derivatives have been synthesized by a short, efficient, and conceptually novel approach. Their copper(I
