313402-16-3

Basic information

• Product Name: 3-(1H-BENZOIMIDAZOL-2-YL)-4-CHLORO-PHENYLAMINE
• Synonyms: 3-(1H-BENZOIMIDAZOL-2-YL)-4-CHLORO-PHENYLAMINE;AKOS BB-7976;ASISCHEM T31067;ART-CHEM-BB B025063;LABOTEST-BB LT00524484;TIMTEC-BB SBB007293;3-(1H-benzo[d]imidazol-2-yl)-4-chloroaniline;3-(1H-Benzo[d]iMidazol-2-yl)-4-chlorobenzenaMine
• CAS NO: 313402-16-3
• Molecular Formula: C₁₃H₁₀ClN₃
• Molecular Weight: 243.69
• EINECS: 200-589-5
• Mol File: 313402-16-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 209-210 °C
• Boiling Point: 513.2°Cat760mmHg
• Flash Point: 264.2°C
• Appearance: /
• Density: 1.395g/cm³
• Vapor Pressure: 1.21E-10mmHg at 25°C
• Refractive Index: 1.738
• Storage Temp.: 2-8°C
• PKA: 11.01±0.10(Predicted)
• CAS DataBase Reference: 3-(1H-BENZOIMIDAZOL-2-YL)-4-CHLORO-PHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1H-BENZOIMIDAZOL-2-YL)-4-CHLORO-PHENYLAMINE(313402-16-3)
• EPA Substance Registry System: 3-(1H-BENZOIMIDAZOL-2-YL)-4-CHLORO-PHENYLAMINE(313402-16-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 313402-16-3(Hazardous Substances Data)

Usage

General Description

3-(1H-benzoimidazol-2-yl)-4-chloro-phenylamine is a chemical compound with the molecular formula C13H10ClN3. It is an organic compound that contains a benzimidazole ring and a chlorophenyl group. This chemical is commonly used in laboratory research and drug development due to its potential pharmacological properties. It has been studied for its potential as an anti-cancer agent and as an inhibitor of certain enzymes. Additionally, it has been investigated for its potential use in treating various neurological disorders. The compound's structure and properties make it a valuable tool for researchers and pharmaceutical developers in the quest for new drugs and treatments.

InChI:InChI=1/C13H10ClN3/c14-10-6-5-8(15)7-9(10)13-16-11-3-1-2-4-12(11)17-13/h1-7H,15H2,(H,16,17)

Upstream product

• 54255-79-7 2-(2-chloro-5-nitrophenyl)-1H-benzo[d]imidazole 
• 349406-06-0 2-chloro-5-nitro-N-(2-nitrophenyl)benzamide 
• 25784-91-2 2-chloro-5-nitrobenzoylchloride 
• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 54255-74-2 N-(2-aminophenyl)-2-chloro-5-nitrobenzamide 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 1185108-74-0 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-(dimethylamino)benzamide 
• 1185108-84-2 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-fluorobenzamide 
• 1185108-78-4 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-cyanobenzamide 
• 1185108-89-7 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-3-(trifluoromethyl)benzamide 
• 496793-78-3 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-3,4,5-trimethoxybenzamide 
• 420828-12-2 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-benzamide 
• 1184871-66-6 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-chlorobenzamide 
• 420826-66-0 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-4-methoxybenzamide 
• 496794-60-6 N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-2-methoxybenzamide 

Relevant articles and documents

Preparation method and application of antibacterial drugs

The invention provides phosphite ester compounds with an antibacterial effect and represented by a general formula I, a preparation method of the compounds, an application of the compounds in antibacterial drugs and pharmaceutical compositions containing the compounds. The ten synthesized compounds are novel in structure, the antibacterial activity of the compounds is equivalent to or even superior to that of positive control clindamycin and ciprofloxacin, the antibacterial spectrum is wide, and the compounds 5 and 10 are particularly expected to be further developed into antibacterial activedrugs.

N - 3 - benzimidazole thiazole derivative and its preparation method and application

The invention discloses a new compound N-3-benzimidazole thiazole amine derivative and a preparation method and application thereof. A structural formula of the compound is shown as in figure I, and in the figure I, R1 is morpholinyl, piperidyl, N-methyl piperazinyl, N-arylpiperazine, diethylin, ethyoxyl, (dimethoxy)ethylamino, or R1 is one of mono-substituted or multi-substituted aniline on the following benzene ring: fluorine, chlorine, trifluoromethoxyl, methyl, methoxyl, hydroxyl group, nitryl, amino group, acetamido, trifluoromethyl and cyano group. The compound disclosed by the invention has better antineoplastic activity, and can be used as a therapeutic agent for treating a tumor in the field of antineoplastic drug preparation.

A second group of the benzimidazole aryl amide compound and its synthesis and use

The invention relates to a diaryl amide compound containing benzimidazole group as well as the synthesis and application of the diaryl amide compound and belongs to the field of chemical medicine. The compound has a general formula I shown in the specific