313546-18-8 Usage
Description
2-METHYL-4-CYANOPHENYLBORONIC ACID is an organic compound that features a boronic acid group attached to a methylated and cyanated phenyl ring. This unique structure endows it with versatile reactivity and properties, making it a valuable building block in organic synthesis and a component in the development of various chemical applications.
Uses
Used in Organic Synthesis:
2-METHYL-4-CYANOPHENYLBORONIC ACID is used as a reactant in the synthesis of oligo-boronic acid receptors. These receptors exhibit improved structural and electronic properties, which can be advantageous for various applications, such as sensing, catalysis, and molecular recognition.
Used in Pharmaceutical Chemistry:
In the pharmaceutical industry, 2-METHYL-4-CYANOPHENYLBORONIC ACID is used as a key intermediate in the synthesis of aminoalkoxybiphenylnitriles. These compounds serve as histamine-3 receptor ligands, which have potential therapeutic applications in the treatment of various conditions, including allergies and cognitive disorders.
Used in Material Science:
2-METHYL-4-CYANOPHENYLBORONIC ACID can also be utilized in the development of new materials with tailored properties. Its incorporation into polymers or other materials can lead to the creation of advanced materials with improved characteristics, such as enhanced stability, selectivity, or conductivity, depending on the specific application.
Check Digit Verification of cas no
The CAS Registry Mumber 313546-18-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,3,5,4 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 313546-18:
(8*3)+(7*1)+(6*3)+(5*5)+(4*4)+(3*6)+(2*1)+(1*8)=118
118 % 10 = 8
So 313546-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H8BNO2/c1-6-4-7(5-10)2-3-8(6)9(11)12/h2-4,11-12H,1H3
313546-18-8Relevant articles and documents
Enthalpy-entropy compensation combined with cohesive free-energy densities for tuning the melting temperatures of cyanobiphenyl derivatives
Dutronc, Thibault,Terazzi, Emmanuel,Guenee, Laure,Buchwalder, Kerry-Lee,Spoerri, Aurore,Emery, Daniel,Mareda, Jiri,Floquet, Sebastien,Piguet, Claude
, p. 8447 - 8456 (2013/07/19)
This work illustrates how minor structural perturbations produced by methylation of 4′-(dodecyloxy)-4-cyanobiphenyl leads to enthalpy-entropy compensation for their melting processes, a trend which can be analyzed within the frame of a simple intermolecular cohesive model. The transformation of the melting thermodynamic parameters collected at variable temperatures into cohesive free-energy densities expressed at a common reference temperature results in a novel linear correlation, from which melting temperatures can be simply predicted from molecular volumes. In tune with temperature! The transformation of the melting thermodynamic parameters into cohesive free-energy densities (CFED) for 4′-(n-oxy)-i′-methyl-j-methyl-4-cyanobiphenyl (CnLi′,j) provides a novel linear correlation for predicting melting temperatures in a simple way. Copyright
Modular Solid-Phase Synthetic Approach to Optimize Structural and Electronic Properties of Oligoboronic Acid Receptors and Sensors for the Aqueous Recognition of Oligosaccharides
Stones, Duane,Manku, Sukhdev,Lu, Xiaosong,Hall, Dennis G.
, p. 92 - 100 (2007/10/03)
This article describes the design and optimization of the first entirely modular, parallel solid-phase synthetic approach for the generation of well-defined polyamine oligoboronic acid receptors and fluorescence sensors for complex oligosaccharides. The s