31384-90-4

Basic information

• Product Name: BZ-GLY-GLY-GLY-OH
• Synonyms: N-BENZOYL-GLY-GLY-GLY;BENZOYL-GLY-GLY-GLY;BENZOYL-GLYCYL GLYCYL GLYCINE;ANGIOTENSIN CONVERTING ENZYME SUBSTRATE;BZ-GLY-GLY-GLY;BZ-GLY-GLY-GLY-OH;HIP-GLY-GLY-OH;HIPPURYL-GLYCYL-GLYCINE
• CAS NO: 31384-90-4
• Molecular Formula: C₁₃H₁₅N₃O₅
• Molecular Weight: 293.28
• Mol File: 31384-90-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 788.3°Cat760mmHg
• Flash Point: 430.6°C
• Appearance: /
• Density: 1.34g/cm³
• Vapor Pressure: 3.46E-26mmHg at 25°C
• Refractive Index: 1.57
• Storage Temp.: -15°C
• CAS DataBase Reference: BZ-GLY-GLY-GLY-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BZ-GLY-GLY-GLY-OH(31384-90-4)
• EPA Substance Registry System: BZ-GLY-GLY-GLY-OH(31384-90-4)

Safety Data

• Hazardous Substances Data: 31384-90-4(Hazardous Substances Data)

Usage

General Description

BZ-GLY-GLY-GLY-OH is a chemical compound consisting of a benzoyl (BZ) group attached to a chain of three glycine (GLY) amino acids, followed by a hydroxyl (OH) group. BZ-GLY-GLY-GLY-OH is a peptide derivative that may have potential applications in the pharmaceutical and medical industries. Peptides like BZ-GLY-GLY-GLY-OH have been studied for their various biological activities, including antimicrobial, anticancer, and antiviral properties. Additionally, BZ-GLY-GLY-GLY-OH may also have potential as a drug delivery system or as a building block for the synthesis of more complex peptide-based drugs. Further research is needed to fully understand the chemical and biological properties of BZ-GLY-GLY-GLY-OH and its potential applications.

InChI:InChI=1/C13H15N3O5/c17-10(15-8-12(19)20)6-14-11(18)7-16-13(21)9-4-2-1-3-5-9/h1-5H,6-8H2,(H,14,18)(H,15,17)(H,16,21)(H,19,20)

Upstream product

• 57461-31-1 hippuroyl azide 
• 13059-60-4 glycylglycine hydrochloride 
• 556-33-2 glycine-glycine-glycine 
• 98-88-4 benzoyl chloride 
• 56-40-6 glycine 
• 63221-10-3 N-(N-benzoyl-glycyl)-glycine hydrazide 

Downstream Products

• 97417-09-9 N-benzoyl-glycyl=>glycyl=>glycine ethyl ester 
• 102451-51-4 1-(N-hippuroyl-glycyl)-2-thioxo-imidazolidin-4-one 
• 1037569-90-6 C₃₄H₃₈N₈O₈ 
• 1037570-06-1 C₃₈H₃₈N₈O₉ 

Relevant articles and documents

Linear energy correlations and failures in the low-energy tandem mass spectra of protonated N-benzoylated tripeptides: Tools for probing mechanisms of CAD processes

The backbone cleavages for three series of protonated N-benzoyl tripeptide ions were studied in a hybrid tandem mass spectrometer: (i) benzoyl-Gly-Gly-Xxx, where Xxx = Gly, Ala, Val, Leu, Ile, Phe, Tyr, Met, Glu, Pro and Trp, (ii) benzoyl-Gly-Xxx-Gly, where Xxx = Gly, Ala, Leu, Phe, Tyr, Met and Trp, and (iii) benzoyl-Xxx-Gly-Gly, where Xxx = Gly, Ale, Val, Leu, Ile, Phe, Tyr, Met, Pro and Trp. C-Terminal γ-type ions and N-terminal a- and b-type ions were noted in all three cases. For benzoyl-Gly-Gly-Xxx, a linear relationship between log(γ1/b2) and the proton affinity of the C-terminal amino acid substituents was found: as the proton affinity of the C-terminal residue increases, the fraction of γ1 ion formation increases. A similar relationship was noted for the benzoyl-Xxx-Gly-Gly tripeptides between log (γ2/b1) and the proton affinity of the N-terminal amino acid substituent: as the proton affinity of the N-terminal residue increases, the fraction of b1 ion formation increases. For the series benzoyl-Gly-Xxx-Gly, these relationships did not hold true. These observations point to similar reaction pathways throughout the benzoyl-Gly-Gly-Xxx series and also similar pathways throughout the benzoyl-Xxx-Gly-Gly, but pathways that are substituent dependent for benzoyl-Gly-Xxx-Gly. The increased correlation coefficients for benzoyl-Gly-Gly-Xxx and benzoyl-Xxx-Gly-Gly when compared with the free tripeptides, suggest that fewer interfering competitive reactions exist, as fewer possibilities for internal hydrogen bonding exist in the N-benzoyl derivatives versus the free compounds.