3139-29-5

Basic information

• Product Name: N-(4-METHOXYPHENYL)-N-(THIEN-2-YLMETHYL)AMINE
• Synonyms: N-(4-methoxyphenyl)-N-(2-thienylmethyl)amine
• CAS NO: 3139-29-5
• Molecular Formula: C₁₂H₁₃NOS
• Molecular Weight: 219.3
• Mol File: 3139-29-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 352.2°Cat760mmHg
• Flash Point: 166.8°C
• Appearance: /
• Density: 1.197g/cm³
• Vapor Pressure: 3.9E-05mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: N-(4-METHOXYPHENYL)-N-(THIEN-2-YLMETHYL)AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-METHOXYPHENYL)-N-(THIEN-2-YLMETHYL)AMINE(3139-29-5)
• EPA Substance Registry System: N-(4-METHOXYPHENYL)-N-(THIEN-2-YLMETHYL)AMINE(3139-29-5)

Safety Data

• Hazardous Substances Data: 3139-29-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H13NOS/c1-14-11-6-4-10(5-7-11)13-9-12-3-2-8-15-12/h2-8,13H,9H2,1H3

Upstream product

• 765-50-4 2-Chloromethylthiophene 
• 104-94-9 4-methoxy-aniline 
• 98-03-3 thiophene-2-carbaldehyde 
• 13533-27-2 4-methoxy-N-(thiophen-2-ylmethylene)aniline 
• 636-72-6 2-thiophenemethanol 

Downstream Products

• 116360-55-5 6-[(4-Methoxy-phenyl)-thiophen-2-ylmethyl-amino]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidine-5-carbaldehyde 
• 1305892-20-9 2-((4-methoxyphenyl)amino)-2-(thiophen-2-yl)acetonitrile 
• 1507344-50-4 C₁₃H₁₂N₂OS 

Relevant articles and documents

Novel N-Alkylbenzimidazole-Ruthenium (II) complexes: Synthesis and catalytic activity of N-alkylating reaction under solvent-free medium

In this article, direct N-alkylation reactions of amines with alcohols derivatives have been investigated. For this purpose, a new series ruthenium (II) complexes bearing N-coordinated benzimidazole complexes with have been synthesized and fully characterized by elemental analysis, FT-IR, 1H NMR and, 13C NMR spectroscopies. Additionally, the structures of the complexes 2b and 2c have been confirmed by X-ray crystallography. Although the N-alkylating reaction is usually performed in toluene, the catalytic study of complexes 2a-d has carried out no additional solvent and alcohol acted both as solvent and reactant of alkylating by using a little excess of alcohols. Surprisingly, conversion and selectivity of amine product for alkylation reaction have been seen high in medium solvent-free relative to in toluene.

A simple method for the synthesis of 1,3-diaminopropan-2-ols derivatives and their ex vivo relaxant activity on isolated rat tracheal rings

Abstract: A mild and eco-friendly method has been developed for the synthesis of a series of 1,3-diaminopropan-2-ols 8a–n. The epoxide of epichlorohydrin undergoes ring-opening with amines using MgSO4 or mixed metal oxides catalysts under mild

Ruthenium-catalyzed reductive amination without an external hydrogen source

A ruthenium-catalyzed reductive amination without an external hydrogen source has been developed using carbon monoxide as the reductant and ruthenium(III) chloride (0.008-2 mol %) as the catalyst. The method was applied to the synthesis of antianxiety agent ladasten.