314769-04-5

Basic information

• Product Name: 2-(3'-Methoxyphenyl)-6-methoxy-4-quinazolinone
• CAS NO: 314769-04-5
• Molecular Weight: 282.299
• Mol File: 314769-04-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3'-Methoxyphenyl)-6-methoxy-4-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3'-Methoxyphenyl)-6-methoxy-4-quinazolinone(314769-04-5)
• EPA Substance Registry System: 2-(3'-Methoxyphenyl)-6-methoxy-4-quinazolinone(314769-04-5)

Safety Data

• Hazardous Substances Data: 314769-04-5(Hazardous Substances Data)

Upstream product

• 1882-71-9 2-amino-5-methoxybenzamide 
• 591-31-1 3-methoxy-benzaldehyde 

Relevant articles and documents

2-phenyl-4-quinazolinone compounds, 2-phenyl-4-alkoxy-quinazoline compounds and their pharmaceutical compositions

Two series of 6,7,2′,3′,4′,5′-substituted 2-phenyl-4-quinazolinones and 6,2′,3′,4′,5′-substituted 2,3-dihydro-2-phenyl-4-quinazolinones are synthesized and evaluated for cytotoxicity against a panel of human tumor cell lines, such as epidermoid carcinoma of the nasopharynx (KB), lung carcinoma (A-549), ileocecal carcinoma (HCT-8), breast cancer (MCF-7), melanoma (SKMEL-2), ovarian cancer (1A9), glioblastoma (U-87-MG), bone (HOS), P-gp-expressing epidermoid carcinoma of the nasopharynx (KB-VIN), and prostate cancer (PC3) cell lines, and some of the compounds are found potent. The present invention also synthesizes 2-phenyl-4-alkoxy-quinazoline compounds, wherein some of the compounds exhibit antiplatelet activity.