3152-16-7

Basic information

• Product Name: 2,5-Furandione, 3-(4-methylphenyl)-
• CAS NO: 3152-16-7
• Molecular Formula: C11H8O3
• Molecular Weight: 188.183
• Mol File: 3152-16-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2,5-Furandione, 3-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Furandione, 3-(4-methylphenyl)-(3152-16-7)
• EPA Substance Registry System: 2,5-Furandione, 3-(4-methylphenyl)-(3152-16-7)

Safety Data

• Hazardous Substances Data: 3152-16-7(Hazardous Substances Data)

Usage

Appearance

White crystalline solid

Solubility

Soluble in organic solvents

Industrial applications

+ Reactant in the production of high-performance resins
+ Cross-linking agent in the synthesis of polymers
+ Building block in the production of drugs and pharmaceutical intermediates

Potential applications

Bio-based platform chemical due to its renewable source and versatility in chemical transformations

Upstream product

• 541-59-3 maleiimide 
• 106-49-0 p-toluidine 
• 110-16-7 maleic acid 
• 201230-82-2 carbon monoxide 
• 766-97-2 4-n-methylphenylacetylene 
• 108-31-6 maleic anhydride 
• 624-31-7 4-tolyl iodide 
• 5524-56-1 ethyl 2-p-tolyl-2-oxoacetate 
• 108-24-7 acetic anhydride 
• 124-38-9 carbon dioxide 
• 98-59-9 p-toluenesulfonyl chloride 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 459-44-9 4-methylbenzenediazonium tetrafluoroborate 

Downstream Products

• 87292-74-8 1-(4-Methylphenyl)-2-chlor-maleinsaeureanhydrid 
• 87292-93-1 2-(4-Methylphenyl)-3-phenoxy-N-phenyl-maleinimid 
• 87292-99-7 3,3'-Thiobis-2-(4-methylphenyl)-N-phenyl-maleinimid 
• 80775-56-0 3,3'-Aminobis-2-(4-methylphenyl)-N-phenyl-maleinimid 
• 87293-02-5 3,3'-Bis-2-(4-methylphenyl)-N-phenyl-maleinimid 
• 87293-03-6 2-(4-Methylphenyl)-3-triphenylphosphanimino-N-phenyl-maleinimid 
• 87292-96-4 2-(4-Methylphenyl)-3-(1-phenyl-3-methyl-pyrazol-5-on-4-yl)-N-phenyl-maleinimid 
• 87292-95-3 2-(4-Methylphenyl)-3-(5,5-dimethylcyclohexan-1,3-dion-2-yl)-N-phenyl-maleinimid 
• 87292-92-0 2-(4-Methylphenyl)-3-(O,O'-dimethyl-dithiophosphoryl)-N-phenyl-maleinimid 
• 87292-91-9 2-(4-Methylphenyl)-3-ethoxythiocarbonylthio-N-phenyl-maleinimid 
• 87292-88-4 2-(4-Methylphenyl)-3-benzylamino-N-phenyl-maleinimid 
• 87292-98-6 1-Phenyl-3-(4-methylphenyl)-pyrrolo<2,3-b>benzothiazin-2-on 
• 87292-97-5 1-Phenyl-3-(4-methylphenyl)-pyrrolo<2,3-b>chinoxalin-2-4H-on 
• 87292-90-8 2-(4-Methylphenyl)-3-phenylthio-N-phenyl-maleinimid 

Relevant articles and documents

Approach to the Synthesis of Unsymmetrical/Symmetrical Maleimides via Desulfitative Arylation at Different Temperatures

New routes toward selective synthesis of both mono-and diaryl maleimides have been innovated. The mere requirement to this end is through the increase of temperature. The method works effectively for maleic anhydride and maleic acid as well. Also, the fir

Asymmetric hydrogenation of maleic anhydrides catalyzed by Rh/bisphosphine-thiourea: efficient construction of chiral succinic anhydrides

Asymmetric hydrogenation of various 3-substituted maleic anhydrides catalyzed by Rh/bisphosphine-thiourea (ZhaoPhos) under mild conditions was successfully developed. A wide range of 3-alkyl and 3-aryl maleic anhydrides were hydrogenated well to provide the desired products 3-substituted succinic anhydrides in one hour with excellent results (full conversions, up to 99% yield, 99% ee, 3000 TON). Importantly, we developed a creative and efficient synthetic route to construct the key intermediate of the hypoglycemic drug mitiglinide through our catalytic system.

A simple, convenient method for the synthesis of maleic anhydrides from α-keto esters and alkanoic acid anhydrides using the TiCl 4/n-Bu3N reagent system

Reaction of α-keto esters with alkanoic acid anhydrides using the TiCl4/n-Bu3N reagent system gives the corresponding maleic anhydrides in 62-95% yields.