31554-15-1

Basic information

• Product Name: 2,3-BIS(HYDROXYMETHYL)NAPHTHALENE
• Synonyms: RARECHEM AL BD 0258;2,3-NAPHTHALENEDIMETHANOL;2,3-BIS(HYDROXYMETHYL)NAPHTHALENE;2,3-Bis(hydroxymethyl)naphtalene;Bishydroxymethylnaphtalene;2,3-BIS(HYDROXYMETHYL)NAPHTHALENE 96+%;Naphthalene-2,3-dimethanol;naphthalene-2,3-diyldimethanol
• CAS NO: 31554-15-1
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.22
• Mol File: 31554-15-1.mol
• Article Data: 23

Chemical Properties

• Melting Point: 157 °C
• Boiling Point: 400.9 °C at 760 mmHg
• Flash Point: 201.5 °C
• Appearance: /
• Density: 1.244g/cm³
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 2,3-BIS(HYDROXYMETHYL)NAPHTHALENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-BIS(HYDROXYMETHYL)NAPHTHALENE(31554-15-1)
• EPA Substance Registry System: 2,3-BIS(HYDROXYMETHYL)NAPHTHALENE(31554-15-1)

Safety Data

• Hazardous Substances Data: 31554-15-1(Hazardous Substances Data)

Usage

Description

2,3-BIS(HYDROXYMETHYL)NAPHTHALENE, also known as Naphthalene-2,3-bis(hydroxymethyl), is an organic compound with the chemical formula C11H12O2. It is a beige solid that serves as an intermediate in the synthesis of various chemical compounds.

Uses

Used in Chemical Synthesis:
2,3-BIS(HYDROXYMETHYL)NAPHTHALENE is used as an intermediate in the preparation of Naphthalene-2,3-dicarboxaldehyde (N356000), which is a key compound in the production of various organic chemicals and pharmaceuticals.
Used in Pharmaceutical Industry:
2,3-BIS(HYDROXYMETHYL)NAPHTHALENE is used as a building block for the synthesis of pharmaceutical compounds, owing to its unique chemical structure and reactivity.
Used in Dye Industry:
2,3-BIS(HYDROXYMETHYL)NAPHTHALENE is used as an intermediate in the production of dyes and pigments, due to its ability to form colored compounds upon further chemical reactions.
Used in Polymer Industry:
2,3-BIS(HYDROXYMETHYL)NAPHTHALENE is used as a monomer in the synthesis of polymers, which can be utilized in various applications such as plastics, coatings, and adhesives.

Upstream product

• 716-39-2 2,3-Naphthalenedicarboxylic anhydride 
• 131866-37-0 2,3-bis-acetoxymethyl-naphthalene 
• 2169-87-1 naphthalene-2,3-dicarboxylic acid 
• 7149-49-7 2,3-naphthalenedicarboxaldehyde 
• 13728-34-2 dimethyl 2,3-naphthalenedicarboxylate 
• 887256-19-1 methyl 1-(t-butyldimethylsilyloxy)-3-[(methoxycarbonyloxy)methyl]-1,4-dihydronaphthalene-2-carboxylate 
• 35447-99-5 1,2-dihydrobenzocyclobuten-1-ol 
• 92912-42-0 7-(t-butyldimethylsilyloxy)bicyclo[4.2.0]octa-1,3,5-triene 
• 13209-15-9 1,2-bis(dibromomethyl)benzene 
• 38998-33-3 2,3-di(bromomethyl)naphthalene 
• 50919-54-5 naphthalene-2,3-dicarboxylic acid diethyl ester 
• 612-12-4 o-Xylylene dichloride 
• 643-79-8 o-phthalic dicarboxaldehyde 

Downstream Products

• 7149-49-7 2,3-naphthalenedicarboxaldehyde 
• 38998-33-3 2,3-di(bromomethyl)naphthalene 
• 110195-13-6 2-phenyl-2,3,3a,4,11,11a-hexahydro-1H-naphtho[2,3-f]isoindole-1,3-dione 
• 190315-16-3 3-O-benzyl-7-(5',6'-benzo-2'-spiroindanyl)oxymorphone 
• 156568-76-2 3-O-benzyl-7-(5',6'-benzo-2'-spiroindanyl)naltrexone 
• 1311140-93-8 C₁₈H₁₂O₆S 
• 1311140-81-4 C₂₂H₂₀O₆S 
• 1316054-13-3 (E)-3-[(2-hydroxy-3-nitrocyclohex-2-en-1-yliden)methyl]-naphthalene-2-carbaldehyde 
• 1379772-66-3 triisopropyl(3-phenylanthracen-2-yloxy)silane 
• 76197-35-8 anthracene-2,3 dicarboxaldehyde 

Relevant articles and documents

1H NMR Study of Two Tetrahydrocyclodecabiphenylenes

5,6,9,10-Tetradehydrobenzocyclodecabiphenylene (2) and 5,6,9,10-tetrahydronaphthocyclodecabiphenylene (3) were prepared by a "bis-Wittig reaction between 1,8-bis((triphenylphosphoranylidene)methyl)biphenylene (5) an

A Unified Catalytic Asymmetric (4+1) and (5+1) Annulation Strategy to Access Chiral Spirooxindole-Fused Oxacycles

A unified catalytic asymmetric (N+1) (N=4, 5) annulation reaction of oxindoles with bifunctional peroxides has been achieved in the presence of a chiral phase-transfer catalyst (PTC). This general strategy utilizes peroxides as unique bielectrophilic four- or five-atom synthons to participate in the C?C and the subsequent umpolung C?O bond-forming reactions with one-carbon unit nucleophiles, thus providing a distinct method to access the valuable chiral spirooxindole-tetrahydrofurans and -tetrahydropyrans with good yields and high enantioselectivities under mild conditions. DFT calculations were performed to rationalize the origin of high enantioselectivity. The gram-scale syntheses and synthetic utility of the resultant products were also demonstrated.

Iron(II) pincer-catalyzed synthesis of lactones and lactams through a versatile dehydrogenative domino sequence

The synthesis of lactones and lactams by using iron(II) pincer-catalyzed dehydrogenative methodology was developed. Starting from 1,n-diols or 1,n-amino alcohols, this domino transformation takes place through initial dehydrogenation of the substrates, subsequent intramolecular cyclization, and final oxidation to afford the desired products in good yields. The ability to access heterocycles of different sizes makes this protocol especially versatile, in which two consecutive oxidation reactions are performed without requiring an external oxidant. In this paper, we report the application of the Fe-MACHO-BH complex [carbonylhydrido(tetrahydroborato)[bis(2-diisopropylphosphinoethyl)amino]iron(II)] in this atom-efficient and environmentally benign process, for which molecular hydrogen is formed as the only stoichiometric side product. Just a little pinch: The iron(II) pincer-catalyzed synthesis of lactones and lactams from easily available 1,n-diols and 1,n-amino alcohols is explored. The use of a nontoxic metal as well as the generation of molecular hydrogen as the only stoichiometric byproduct makes this method a highly atom-efficient and environmentally benign process.