31554-48-0

Basic information

• Product Name: 3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE
• Synonyms: AKOS BBS-00004851;AKOS MSC-0120;3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE;3-BROMOMETHYL-2,5-DIHYDROTHIOPHENE-1,1-DIOXIDE
• CAS NO: 31554-48-0
• Molecular Formula: C₅H₇BrO₂S
• Molecular Weight: 211.08
• Mol File: 31554-48-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 87-88 °C(Solv: ethanol (64-17-5))
• Boiling Point: 342.9°Cat760mmHg
• Flash Point: 161.2°C
• Appearance: /
• Density: 1.747g/cm³
• Vapor Pressure: 0.000145mmHg at 25°C
• Refractive Index: 1.565
• CAS DataBase Reference: 3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE(31554-48-0)
• EPA Substance Registry System: 3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE(31554-48-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 31554-48-0(Hazardous Substances Data)

Usage

Description

3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE is an organic compound that serves as a reagent in the synthetic preparation of gelsemine, a natural alkaloid with potential therapeutic applications.
Used in Pharmaceutical Industry:
3-(BROMOMETHYL)-2,5-DIHYDRO-1H-1-LAMBDA6-THIOPHENE-1,1-DIONE is used as a synthetic reagent for the preparation of gelsemine, which is utilized in the development of treatments for pathological anxiety. Its role in the synthesis process is crucial for producing gelsemine, a compound with potential anxiolytic properties that can help address anxiety disorders.

InChI:InChI=1/C5H7BrO2S/c6-3-5-1-2-9(7,8)4-5/h1H,2-4H2

Upstream product

• 1193-10-8 3-methyl-2,5-dihydrothiophen-1,1-dioxide 

Downstream Products

• 23691-13-6 2-(bromomethyl)buta-1,3-diene 
• 84369-87-9 2-(phenylthiylmethyl)-1,3-butadiene 
• 39565-78-1 3-Phenylaminomethyl-3-sulfolen 
• 100961-06-6 3-ethoxymethyl-2,5-dihydro-thiophene-1,1-dioxide 
• 123848-82-8 3-(phenylthiomethyl)-3-sulfolene 
• 14314-21-7 (+/-)-ipsenol 
• 61345-99-1 4-methyl-3-methylene-4-penten-2-one 

Relevant articles and documents

Diversity oriented approach to phenylalanine derivatives via the dielsalder reaction involving sulfolene intermediates

We report a new synthetic approach to highly functionalized phenylalanine derivatives via sulfolenes as latent diene equivalents. Here, the DielsAlder reaction has been used as a key step to assemble diverse unusual amino acid derivatives.

Pesticidal phosphoryl- and phosphinyl-thioalkyl cyclic sufones

Compounds of the formula: STR1 wherein X is sulfur or oxygen; R1 is lower alkyl; R2 is lower alkyl, lower straight chain alkoxy, lower alkylthio, phenyl or the group --NR3 R4 where R3 and R4 are independently hydrogen or lower alkyl, provided that when X is oxygen, R2 is not phenyl, are pesticidal, exhibiting activity against pests such as plant fungal diseases and, in many cases, insects.