3156-21-6

Basic information

• Product Name: 2-(2,4-Dichloro-phenoxymethyl)-1H-benzoimidazole
• Synonyms: 2-(2,4-Dichloro-phenoxymethyl)-1H-benzoimidazole;2-((2,4-dichlorophenoxy)methyl)-1H-benzo[d]imidazole
• CAS NO: 3156-21-6
• Molecular Formula: C₁₄H₁₀Cl₂N₂O
• Molecular Weight: 293.15
• Mol File: 3156-21-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 175 °C
• Boiling Point: 519.9°Cat760mmHg
• Flash Point: 268.2°C
• Appearance: /
• Density: 1.439g/cm³
• Vapor Pressure: 2.17E-10mmHg at 25°C
• Refractive Index: 1.686
• PKA: 11.29±0.10(Predicted)
• CAS DataBase Reference: 2-(2,4-Dichloro-phenoxymethyl)-1H-benzoimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-Dichloro-phenoxymethyl)-1H-benzoimidazole(3156-21-6)
• EPA Substance Registry System: 2-(2,4-Dichloro-phenoxymethyl)-1H-benzoimidazole(3156-21-6)

Safety Data

• Hazardous Substances Data: 3156-21-6(Hazardous Substances Data)

Usage

Type of medication

Anthelmintic

Target animals

Dogs, cats, horses, and livestock

Mechanism of action

Interferes with the parasite's ability to absorb glucose

Result

Death of the parasite

Safety

Relatively safe for use in animals when administered at recommended dosages

Potential additional use

Anticancer properties in humans (as shown in recent studies)

InChI:InChI=1/C14H10Cl2N2O/c15-9-5-6-13(10(16)7-9)19-8-14-17-11-3-1-2-4-12(11)18-14/h1-7H,8H2,(H,17,18)

Upstream product

• 94-75-7 2,4-Dichlorophenoxyacetic acid 
• 95-54-5 1,2-diamino-benzene 
• 4857-04-9 2-chloromethyl-1H-benzimidazole 
• 120-83-2 2,4-dichlorophenol 

Relevant articles and documents

1-ethyl gallate-2-substituted phenoxymethyl benzimidazoles: Synthesis, molecular structure, antimicrobial activities and complex with Cr(III)

Summary: The design of gallate and benzimidazole containing derivatives is expected to produce new bioactive molecules with multiple applications. Here the synthesis of eight novel benzimidazole compounds containing ethyl gallate and substituted phenoxyme

A rapid and convenient synthesis of derivatives of imidazoles under Microwaveirradiation

Anefficient and a quick microwave-assisted synthesis of benzimidazoles and trisubstituted imidazoles was developed. Three benzimidazoles were obtained as a result of the condensation of 1,2-phenylenediamine with carboxylic acids and acetoacetic ester without catalyst. A series of trisubstituted imidazoles were syn thesized by condensation of benzil, aromatical dehyde and ammonium acetate in the presence of glacial acetic acid.