315672-60-7

Basic information

• Product Name: 3-Furancarboxylicacid,2-methyl-,hydrazide(9CI)
• Synonyms: 3-Furancarboxylicacid,2-methyl-,hydrazide(9CI);2-methyl-3-furohydrazide(SALTDATA: FREE);2-methyl-3-furancarbohydrazide;2-methylfuran-3-carbohydrazide
• CAS NO: 315672-60-7
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.14
• Product Categories: AMIDE
• Mol File: 315672-60-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 149.5-150 °C
• Appearance: /
• Density: 1.207g/cm³
• Refractive Index: 1.531
• PKA: 12.32±0.10(Predicted)
• CAS DataBase Reference: 3-Furancarboxylicacid,2-methyl-,hydrazide(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Furancarboxylicacid,2-methyl-,hydrazide(9CI)(315672-60-7)
• EPA Substance Registry System: 3-Furancarboxylicacid,2-methyl-,hydrazide(9CI)(315672-60-7)

Safety Data

• Hazardous Substances Data: 315672-60-7(Hazardous Substances Data)

Usage

General Description

3-Furancarboxylicacid,2-methyl-,hydrazide(9CI) is a chemical compound with the molecular formula C6H8N2O2. It is also known as 2-Methyl-3-furoic hydrazide and is a white to off-white crystalline powder. This chemical is used in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in the production of various organic compounds. Additionally, it has been studied for its potential use in the treatment of certain diseases and conditions. However, like all chemicals, it should be handled and used with proper safety precautions to prevent any harm or danger to human health or the environment.

InChI:InChI=1/C6H8N2O2/c1-4-5(2-3-10-4)6(9)8-7/h2-3H,7H2,1H3,(H,8,9)

Upstream product

• 28921-35-9 2-methyl-3-ethoxycarbonyl-furan 
• 6141-58-8 methyl 2-methyl-3-furancarboxylate 

Downstream Products

• 1246010-98-9 C₁₃H₁₂IN₃O₂S 
• 894225-23-1 C₁₄H₁₅N₃O₃S 
• 891085-13-5 C₁₄H₁₅N₃O₂S 
• 438232-76-9 C₁₄H₁₅N₃O₂S 
• 1320340-17-7 C₂₇H₂₆N₆O₆ 
• 891570-59-5 C₁₃H₁₂BrN₃O₂S 
• 306954-97-2 4-ethyl-1-(2-methylfuran-3-yl)carbonylthiosemicarbazide 

Relevant articles and documents

Thermodynamics and Kinetics of the Reaction between Pyridoxal-5-Phosphate and Hydrazides of 2-Methylfuran-3-Carboxylic and Thiophene-3-Carboxylic Acids in an Aqueous Solution

Abstract: The stability constants of pyridoxal-5-phosphate hydrazones formed with 2-methylfuran-3-carbohydrazide and thiophene-3-carbohydrazide in an aqueous solution at pH 1.9, 6.6, 7.0, and 7.4 are determined via spectrophotometry. The kinetics of the processes of formation and hydrolysis of the Schiff bases are studied, and the constant of the direct and reverse reactions are calculated from the electronic absorption spectra. The stability constants of the Schiff bases are calculated from their ratio. The thermodynamic parameters of the reaction of formation (log K, ΔH, and TΔS) of both hydrazones at pH 6.6 are determined via calorimetry. The reasons for the differences between the equilibrium constants calculated from the data of spectrophotometric and kinetic experiments are discussed, and the reliability of the obtained results is analyzed.

Design, synthesis and anti-influenza virus activity of furan-substituted spirothiazolidinones

A new series of N-(3-oxo-1-thia-4-azaspiro[4.5]decan-4-yl)carboxamides have been designed, synthesized and evaluated as antiviral agents. The compounds were prepared by condensation of 2-methylfuran-3-carbohydrazide, appropriate carbonyl compounds and sul

Synthesis, experimental and theoretical study on the structure of some semicarbazides with potential antibacterial activity

A series of 1,4-disubstituted semicarbazide and 4,4'-bis[1-substituted semicarbazide]diphenyl-methane derivatives were synthesized to explore their antibacterial activity. New compounds were characterized by elemental analysis and spectroscopic data. In order to find the tautomeric equilibrium for the molecules energy calculations for each possible tautomeric form of model compound 2, and for the most antibacterially active compound 7 in the investigated series, were calculated for the gas phase at the RHF/SCF/6-31G** level of theory.