31600-54-1

Basic information

• Product Name: 1-Octanol, 8-(phenylmethoxy)-
• CAS NO: 31600-54-1
• Molecular Formula: C15H24O2
• Molecular Weight: 236.354
• Mol File: 31600-54-1.mol
• Article Data: 37

Chemical Properties

• CAS DataBase Reference: 1-Octanol, 8-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Octanol, 8-(phenylmethoxy)-(31600-54-1)
• EPA Substance Registry System: 1-Octanol, 8-(phenylmethoxy)-(31600-54-1)

Safety Data

• Hazardous Substances Data: 31600-54-1(Hazardous Substances Data)

Upstream product

• 629-41-4 1,8-Octanediol 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 91842-56-7 8-(benzyloxy)octyl 2-tetrahydropyranyl ether 

Downstream Products

• 36170-05-5 rubrenolide 
• 186499-06-9 2-[(8Z)-heptadec-8-en-1-yl]benzene-1,4-diol 
• 1447173-32-1 1,17-bis(benzyloxy)-9-oxaheptadecane 

Relevant articles and documents

Nematicidal activity of benzyloxyalkanols against pine wood nematode

Pine wilt disease (PWD) is caused by the pine wood nematode (PWN; Bursaphelenchus xylophilus) and causes severe environmental damage to global pine forest ecosystems. The current strategies used to control PWN are mainly chemical treatments. However, the continuous use of these reagents could result in the development of pesticide-resistant nematodes. Therefore, the present study was undertaken to find potential alternatives to the currently used PWN control agents abamectin and emamectin. Benzyloxyalkanols (BzOROH; R = C2–C9 ) were synthesized and the nematicidal activity of the synthetic compounds was investigated. Enzymatic inhibitory assays (acetylcholinesterase (AChE) and glutathione S-transferase (GST)) were performed with BzOC8OH and BzOC9OH to understand their mode of action. The benzyloxyalkanols showed higher nematicidal activity than did benzyl alcohol. Among the tested BzOROHs, BzC8OH and BzC9OH showed the strongest nematicidal activity. The LD50 values of BzC8OH and BzC9OH were 246.1 and 158.0 ppm, respectively. No enzyme inhibitory activity was observed for BzC8OH and BzC9OH. The results suggested that benzyloxyalcohols could be an alternative nematicidal agent.

Composition for controlling pine wood nematode containing benzyloxyalcohol

The present invention relates to a composition for controlling pine nematode comprising a benzyloxyalcohol compound and a method for controlling pine nematode using the same.

LIPID PRODRUGS OF GLUCOCORTICOIDS AND USES THEREOF

The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.