31652-74-1

Basic information

• Product Name: 2'-O,3'-O,5'-O-Tribenzoylcytidine
• Synonyms: 2'-O,3'-O,5'-O-Tribenzoylcytidine;Cytidine 2',3',5'-tribenzoate
• CAS NO: 31652-74-1
• Molecular Formula: C₃₀H₂₅N₃O₈
• Molecular Weight: 555.53
• Mol File: 31652-74-1.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-O,3'-O,5'-O-Tribenzoylcytidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O,3'-O,5'-O-Tribenzoylcytidine(31652-74-1)
• EPA Substance Registry System: 2'-O,3'-O,5'-O-Tribenzoylcytidine(31652-74-1)

Safety Data

• Hazardous Substances Data: 31652-74-1(Hazardous Substances Data)

Upstream product

• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 18037-10-0 2,4-O,N-bis(trimethylsilyl)cytosine 
• 85743-99-3 N-(2-Trimethylsilanyloxy-pyrimidin-4-yl)-benzamide 
• 151867-55-9 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl methyl carbonate 
• 23624-64-8 N⁴-benzoyl-1-(2’,3’,5’-tri-O-benzoyl-β-D-ribofuranosyl)-cytosine 
• 64339-87-3 N₄,O-bis(trimethylsilyl)-N₄-benzoylcytosine 
• 870135-04-9 4-N-pivalyl-2',3',5'-tri-O-benzoylcytidine 
• 870135-05-0 4-N-trifluoroacetyl-2',3',5'-tri-O-benzoylcytidine 
• 613-90-1 benzoyl cyanide 
• 65-46-3 CYTIDINE 
• 93-97-0 benzoic acid anhydride 
• 115459-50-2 2,3,5-Tri-O-benzoyl-D-ribofuranose 
• 1748-04-5 tribenzoyl uridine 
• 27391-03-3 N⁴-acetyl-O^2'_,O3'_,O5'-tribenzoyl-cytidine 

Downstream Products

• 65-46-3 cytidine 
• 870135-04-9 4-N-pivalyl-2',3',5'-tri-O-benzoylcytidine 
• 870135-05-0 4-N-trifluoroacetyl-2',3',5'-tri-O-benzoylcytidine 
• 1748-04-5 tribenzoyl uridine 
• 154971-71-8 2',3',5'-tri-O-benzoylcytidine 4-N-(O,O-bis(2-cyanoethyl) phosphoramidate) 

Relevant articles and documents

Chemoselective N-Deacetylation of Protected Nucleosides and Nucleotides Promoted by Schwartz's Reagent

Protection and deprotection strategies involving the N-acetyl group are widely utilized in nucleoside and nucleotide chemistry. Herein, we present a mild and selective N-deacetylation methodology, applicable to purine and pyrimidine nucleosides, by means of Schwartz's reagent, compatible with most of the common protecting groups used in nucleoside chemistry.

'Green' methodology for efficient and selective benzoylation of nucleosides using benzoyl cyanide in an ionic liquid

Benzoyl cyanide in the ionic liquid 1-methoxyethyl-3-methylimidazolium methanesulfonate has been employed as a 'green' alternative and mild reaction condition protocol to conventional pyridine-benzoyl chloride system for efficient and selective benzoylation of nucleosides (of both the ribo- and deoxyribo-series) at ambient temperatures. The use of benzoyl cyanide-ionic liquid combination has been successfully extended for highly efficient benzoylation of phenols, aromatic amines, benzyl alcohol, aliphatic diols, 3-aminophenol and 2-aminobenzylalcohol, which indicates the versatility of this benzoylating system.

Hydrothermal deamidation of 4-N-acylcytosine nucleoside derivatives: Efficient synthesis of uracil nucleoside esters

(Chemical Equation Presented) N,O-Peracylated cytidine and 2′-deoxycytidine derivatives in superheated water/DME solutions (oil bath at 125°C) undergo hydrolytic deamidation (and/or N-deacylation). Acylated starting materials derived from arylcarboxylic acids give the corresponding uridine esters cleanly, and such derivatives crystallize selectively from the cooled reaction mixtures in high yields.