3168-01-2

Basic information

• Product Name: HYDROXYHEXAMIDE
• Synonyms: HYDROXYHEXAMIDE;N-[(Cyclohexylamino)carbonyl]-4-(1-hydroxyethyl)benzenesulfonamide;Hydroxyhexamide 3168-01-2
• CAS NO: 3168-01-2
• Molecular Formula: C₁₅H₂₂N₂O₄S
• Molecular Weight: 326.41
• Product Categories: Inhibitors
• Mol File: 3168-01-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 2.37E-11mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: 2-8°C
• CAS DataBase Reference: HYDROXYHEXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: HYDROXYHEXAMIDE(3168-01-2)
• EPA Substance Registry System: HYDROXYHEXAMIDE(3168-01-2)

Safety Data

• Hazardous Substances Data: 3168-01-2(Hazardous Substances Data)

Usage

General Description

Hydroxyhexamide, also known as 2-hydroxyhexanamide, is a chemical compound with the molecular formula C6H13NO2. It is a derivative of hexane and belongs to the amide functional group. Hydroxyhexamide is a white, crystalline powder with a mild odor and is soluble in water. It is commonly used as an intermediate in the production of pharmaceuticals and agrochemicals. Additionally, it has potential applications in the fields of cosmetics and personal care products. Hydroxyhexamide is known for its antimicrobial properties and is often utilized as a preservative in various consumer products to inhibit the growth of bacteria, fungi, and other microorganisms.

InChI:InChI=1/C21H30O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h12,16-18,24H,4-11H2,1-3H3/t16?,17?,18?,19-,20-,21-/m0/s1

Upstream product

• 968-81-0 acetohexamide 
• 220948-18-5 (+/-)-4-(1-acetoxyethyl)-N-(cyclohexylcarbamoyl)benzenesulfonamide 
• 16712-69-9 p-ethylbenzenesulfonyl chloride 
• 1565-17-9 4-acetylbenzenesulfonamide 
• 138-38-5 4-ethylbenzenesulfonamide 
• 113412-15-0 (+/-)-4-(1-hydroxyethyl)benzenesulfonamide 
• 220948-17-4 (+/-)-4-(1-acetoxyethyl)benzenesulfonamide 

Downstream Products

• 220948-24-3 (R)-(+)-4-(1-acetoxyethyl)-N-(cyclohexylcarbamoyl)benzenesulfonamide 

Relevant articles and documents

Metabolic reduction of acetohexamide by rabbit tissue

The in vitro metabolic reduction of acetohexamide was studied using rabbit tissue preparations. Acetohexamide is mainly reduced in the cytosols of rabbit liver and kidney, and its reduction is catalyzed by ketone reductases.

Reduction of drug ketones by dihydrodiol dehydrogenases, carbonyl reductase and aldehyde reductase of human liver

In this study, we compared the enzymatic reduction of 10 drugs with a ketone group by homogeneous carbonyl reductase, aldehyde reductase and three dihydrodiol dehydrogenases of human liver cytosol. At least one and in some cases all of the three dihydrodi