31696-09-0

Basic information

• Product Name: Ethyl 1-Cbz-5-oxoazepane-4-carboxylate
• Synonyms: Ethyl 1-Cbz-5-oxoazepane-4-carboxylate;N-CBZ-5-OXOAZEPANE-4-CARBOXYLIC ACID ETHYL ESTER
• CAS NO: 31696-09-0
• Molecular Formula: C₁₇H₂₁NO₅
• Molecular Weight: 319.35234
• Mol File: 31696-09-0.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 459.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.208±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 11.40±0.20(Predicted)
• CAS DataBase Reference: Ethyl 1-Cbz-5-oxoazepane-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 1-Cbz-5-oxoazepane-4-carboxylate(31696-09-0)
• EPA Substance Registry System: Ethyl 1-Cbz-5-oxoazepane-4-carboxylate(31696-09-0)

Safety Data

• Hazardous Substances Data: 31696-09-0(Hazardous Substances Data)

Usage

General Description

Ethyl 1-Cbz-5-oxoazepane-4-carboxylate is a chemical compound with the molecular formula C15H19NO4. It is a derivative of azepane and contains a carbobenzyloxy (Cbz) group. Ethyl 1-Cbz-5-oxoazepane-4-carboxylate is used in organic synthesis and medicinal chemistry, particularly in the development of pharmaceuticals and agrochemicals. It is also used as a building block in the synthesis of various drugs and biologically active compounds. Its unique structure and reactivity make it a valuable intermediate in the production of diverse chemical compounds with potential therapeutic and agricultural applications.

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 

Downstream Products

• 83621-33-4 benzyl 4-oxoazepane-1-carboxylate 
• 1065113-59-8 benzyl 2-benzyl-4-oxo-5,6,8,9-tetrahydro-7H-pyrimido[4,5-d]azepine-7-carboxylate 
• 1228230-55-4 10-hydroxy-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid benzyl ester 
• 1613666-09-3 2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-ol 
• 1065113-62-3 benzyl 2-benzyl-4-chloro-5,6,8,9-tetrahydro-7H-pyrimido[4,5-d]azepine-7-carboxylate 
• 1065110-62-4 AMG-167 
• 1613666-19-5 C₂₄H₂₅N₃O₃ 
• 1065111-00-3 2-benzyl-4-methoxy-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine 

Relevant articles and documents

Talipexole variations as novel bitopic dopamine D2 and D3receptor ligands

We linked 2-aminothiazoloazepane scaffolds with phenylpiperazine pharmacophores to generate bitopic dopamine receptor ligands. Highest D2R/D3R binding affinities up to pKi values of 7.74 were observed for compounds containing a 1-(2,3-dichlorophenyl)piperazinoyl moiety, maintaining affinity with deaminated 5,6,7,8-tetrahydro-4H-thiazoloazepine derivatives.

INDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF

Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.

BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF

Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of Retinoic Acid Receptor-Related Orphan Receptor regulated diseases and disorders.