3172-42-7

Basic information

• Product Name: SALICYLIDENE O-CHLOROANILINE
• Synonyms: 2-((E)-[(2-Chlorophenyl)imino]methyl)phenol;alpha-(2-Chlorophenylimino)-ortho-cresol;Phenol,2-(((2-chlorophenyl)imino)methyl)-;SALICYLIDENE O-CHLOROANILINE;TIMTEC-BB SBB008058;2-(2-Chlorophenyliminomethyl)phenol;2-[(2-Chlorophenyl)iminomethyl]phenol;2-[[(2-Chlorophenyl)imino]methyl]phenol
• CAS NO: 3172-42-7
• Molecular Formula: C₁₃H₁₀ClNO
• Molecular Weight: 231.68
• Mol File: 3172-42-7.mol
• Article Data: 15

Chemical Properties

• Melting Point: 82-83 °C
• Boiling Point: 372°C at 760 mmHg
• Flash Point: 178.8°C
• Appearance: /
• Density: 1.395g/cm³
• Vapor Pressure: 9.9E-06mmHg at 25°C
• Refractive Index: 1.745
• PKA: 8.28±0.30(Predicted)
• CAS DataBase Reference: SALICYLIDENE O-CHLOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: SALICYLIDENE O-CHLOROANILINE(3172-42-7)
• EPA Substance Registry System: SALICYLIDENE O-CHLOROANILINE(3172-42-7)

Safety Data

• Hazardous Substances Data: 3172-42-7(Hazardous Substances Data)

Usage

General Description

SALICYLIDENE O-CHLOROANILINE, also known as 2-Hydroxybenzaldehyde o-chloroaniline, is a chemical compound that belongs to the class of salicylidene anilines. It is an organic compound with the molecular formula C13H10ClNO2. SALICYLIDENE O-CHLOROANILINE is commonly used in the synthesis of various azo dyes and pigments, as well as in the manufacturing of pharmaceuticals and agrochemicals. It is also known for its antibacterial and antifungal properties, making it a useful ingredient in various personal care and healthcare products. SALICYLIDENE O-CHLOROANILINE is a light yellow crystalline solid with a melting point of 180-182°C and is soluble in organic solvents such as ethanol and chloroform. However, it should be handled with care as it is considered toxic and harmful if swallowed, inhaled, or comes into contact with skin.

InChI:InChI=1/C13H10ClNO/c14-11-6-2-3-7-12(11)15-9-10-5-1-4-8-13(10)16/h1-9,15H

Upstream product

• 90-02-8 salicylaldehyde 
• 95-51-2 o-chloroaniline 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 90-02-8 salicylaldehyde 
• 95-51-2 o-chloroaniline 
• 89-95-2 2-methyl-benzyl alcohol 
• 82056-90-4 MoOCl₃(OHC₆H₄CHNC₆H₄Cl)2 
• 84975-22-4 MoCl₂(ClC₆H₄NCHC₆H₄O)2 
• 82057-01-0 WOCl₃(OHC₆H₄CHNC₆H₄Cl)2 
• 861682-76-0 [RuH(CO)(P(C₆H₅)3)2(C₆H₄ClNCHC₆H₄O)] 
• 53177-47-2 bis(N-2-chlorophenylsalicylidenaminato)copper(II) 
• 1259430-90-4 3H-N-(2-chlorophenyl)-1,2-benzisoxazole 
• 1322617-37-7 N-(3-benzyl-4-((2-chlorophenyl)amino)-2-oxochroman-3-yl)benzamide 
• 1322617-38-8 N-(3-benzyl-4-((2-chlorophenyl)amino)-2-oxochroman-3-yl)benzamide 
• 1360873-48-8 (3aS,4R,9aR)-N-(2-chlorophenyl)-3,3a,4,9a-tetrahydro-2H-furo[2,3-b]chromen-4-amine 

Relevant articles and documents

Palladium-Catalyzed Regioselective C-Benzylation via a Rearrangement Reaction: Access to Benzyl-Substituted Anilines

An unprecedented C-benzylation rearrangement reaction, catalyzed by palladium, is reported. The reaction proceeds by rearrangement leading to the direct synthesis of para or ortho benzyl-substituted N-methylanilines. The product is obtained in high regioselectivity, without the need to use a ligand for the catalytic process.

Synthesis, characterization and antimicrobial activity of copper(II) complexes of some ortho-substituted aniline schiff bases; Crystal structure of Bis(2-methoxy-6-imino)methylphenol copper(II) complex

This study presents the synthesis, characterization and antimicrobial activity of copper(II) complexes of some ortho-substituted aniline Schiff bases (L1-L8). The Schiff bases and their respective copper(II) complexes were characteri

Halide substituted Schiff-bases: Different activities in methyltrioxorhenium(VII) catalyzed epoxidation via different substitution patterns

This report shows the influence of halide substituted Schiff-bases as ligands of methyltrioxorhenium (MTO) in epoxidation catalysis. Therefore, selected Schiff-bases were prepared by the reaction of hydroxy-benzaldehydes and aniline derivates. These differently substituted Schiff-bases were tested as MTO-ligands in cyclooctene-and 1-octene-epoxidation. Although no great disparities among the substitution patterns have been found, some conclusions can be drawn. Flourines are inferior to chlorines or bromines as substituents. Halides in ortho-position lead to higher activities than in para-or meta-position. The balance between electron donating and withdrawing influences at the Schiff-base plays a prominent role in their utility as ligand to MTO in epoxidation catalysis.