317806-81-8

Basic information

• Product Name: methyl 3α,12α-bis(2-((7-benzyloxy)naphthyloxy)acetyloxy)-5β-cholan-24-oate
• Synonyms: methyl 3α,12α-bis(2-((7-benzyloxy)naphthyloxy)acetyloxy)-5β-cholan-24-oate
• CAS NO: 317806-81-8
• Molecular Weight: 987.243
• Mol File: 317806-81-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3α,12α-bis(2-((7-benzyloxy)naphthyloxy)acetyloxy)-5β-cholan-24-oate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3α,12α-bis(2-((7-benzyloxy)naphthyloxy)acetyloxy)-5β-cholan-24-oate(317806-81-8)
• EPA Substance Registry System: methyl 3α,12α-bis(2-((7-benzyloxy)naphthyloxy)acetyloxy)-5β-cholan-24-oate(317806-81-8)

Safety Data

• Hazardous Substances Data: 317806-81-8(Hazardous Substances Data)

Upstream product

• 317806-79-4 ethyl 2-(((7-benzyloxy)naphthalene)oxy)acetate 
• 317806-80-7 2-((7-benzyloxy)naphthyloxy)acetic acid 
• 118495-07-1 7-(benzyloxy)-2-naphthol 
• 3245-38-3 methyl deoxycholate 
• 582-17-2 2,7-Dihydroxynaphthalene 

Relevant articles and documents

Highly diastereoselective synthesis of the 1,1'-binaphthol unit on a bile acid template

The use of 7-deoxycholic acid as a chiral template in the asymmetric syntheses of 1,1'-binaphthyl-2,2'-diol derivatives is reported. Intramolecular coupling of compounds 7 and 11 have been carried out with Mn(acac)3 in CH3CN to afford coupled binaphthol products 8 and 12 with 65% and >99% diastereoselectivity, respectively. In both cases the predominant formation of the (S) isomers were predicted by computer modeling studies. This was confirmed in the case of compound 12.