31819-61-1 Usage
Description
(5S,6R)-(+)-5,6-diphenylpiperazin-2-one, with the molecular formula C16H16N2O, is a piperazine derivative featuring a chiral center. It exists as a pair of enantiomers, with the (5S,6R)-(+)-enantiomer being the active form. This chemical compound is widely recognized for its utility as a pharmaceutical intermediate and its role in the synthesis of various drugs. Its structural attributes and biological activity render it a significant building block for the development of novel pharmaceuticals and research chemicals, particularly in the field of neuropharmacology.
Uses
Used in Pharmaceutical Industry:
(5S,6R)-(+)-5,6-diphenylpiperazin-2-one is utilized as a pharmaceutical intermediate for the development of new drugs. Its unique structure and chirality make it a valuable component in the synthesis process, contributing to the creation of innovative medications with potential applications in various therapeutic areas.
Used in Drug Synthesis:
In the field of drug synthesis, (5S,6R)-(+)-5,6-diphenylpiperazin-2-one serves as a key building block. Its incorporation into the molecular structure of drugs can enhance their efficacy, selectivity, and overall performance, making it an essential tool in the development of novel pharmaceuticals.
Used in Neuropharmacology Research:
(5S,6R)-(+)-5,6-diphenylpiperazin-2-one is employed as a research chemical in neuropharmacology. Its biological activity and structural features make it a promising candidate for studying the mechanisms of action and potential therapeutic applications in the treatment of neurological disorders and conditions.
Used in Chiral Chemistry:
The chiral nature of (5S,6R)-(+)-5,6-diphenylpiperazin-2-one makes it an important compound in chiral chemistry. It can be used to study the effects of stereochemistry on drug action, selectivity, and pharmacokinetics, contributing to a deeper understanding of the role of chirality in drug design and development.
Check Digit Verification of cas no
The CAS Registry Mumber 31819-61-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,8,1 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 31819-61:
(7*3)+(6*1)+(5*8)+(4*1)+(3*9)+(2*6)+(1*1)=111
111 % 10 = 1
So 31819-61-1 is a valid CAS Registry Number.
31819-61-1Relevant articles and documents
Method of asymmetric hydrogenation synthesis of chiral lactam by catalyzing 2-hydroxypyrazine compound with palladium
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Paragraph 0029-0045, (2020/03/17)
The invention provides a method of asymmetric hydrogenation synthesis of chiral lactam by catalyzing 2-hydroxypyrazine compound with palladium. In the formula, R is a C1-C6 alkyl group or an aryl group containing a substituent group being at least one of F, Cl, Br, CF3, Me, MeO, Et and nPr. The method employs feasible raw materials and is high in enantioselectivity of product and high in yield, wherein the enantiomeric excess can reach 90%. The catalyst is low-cost and feasible and is good in air stability, so that the method is a route with good atom economy and environment-friendly effect for the asymmetric hydrogenation synthesis of the chiral lactam from the 2-hydroxypyrazine compound. Meanwhile, the method is simple in operation, is practicable and easy, is high in yield, is environment-friendly and green, is gentle in reaction conditions, and has a potential practical application value.
Synthesis of (1R,2R)-DPEN-derived triazolium salts and their application in asymmetric intramolecular Stetter reactions
Jia, Min-Qiang,Li, Yi,Rong, Zi-Qiang,You, Shu-Li
supporting information; experimental part, p. 2072 - 2074 (2011/05/14)
A series of novel chiral triazolium salts has been synthesized from readily available (1R,2R)-DPEN and found to be efficient for the enantioselective intramolecular Stetter reaction. With 10 mol% of the catalyst, the intramolecular Stetter reaction was re
