318293-54-8Relevant articles and documents
Rigid amphiphiles for membrane protein manipulation
McQuade, D. Tyler,Quinn, Mariah A.,Yu, Seungju M.,Polans, Arthur S.,Krebs, Mark P.,Gellman, Samuel H.
, p. 758 - 761 (2007/10/03)
The two nonhomologous membrane proteins bacteriorhodopsin and bovine rhodopsin can be extracted from their native membranes by the rigid tripod amphiphile 1. Both proteins are maintained in a stable, soluble form, which is a prerequisite for crystallization. This new class of amphiphiles can be easily modified and could prove to be very useful for membrane protein manipulation.