31867-78-4

Basic information

• Product Name: 3-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID
• Synonyms: 3-(PhenylsulfonaMido)propanoic acid
• CAS NO: 31867-78-4
• Molecular Formula: C₉H₁₁NO₄S
• Molecular Weight: 229.25
• Mol File: 31867-78-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 437.7°Cat760mmHg
• Flash Point: 218.5°C
• Appearance: /
• Density: 1.367g/cm³
• Vapor Pressure: 1.96E-08mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID(31867-78-4)
• EPA Substance Registry System: 3-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID(31867-78-4)

Safety Data

• Hazardous Substances Data: 31867-78-4(Hazardous Substances Data)

Usage

General Description

3-[(Phenylsulfonyl)amino]propanoic acid is a chemical compound with the molecular formula C9H11NO4S. It is a derivative of propanoic acid that contains a phenylsulfonyl group and an amino group. 3-[(PHENYLSULFONYL)AMINO]PROPANOIC ACID is used as a pharmaceutical intermediate and is of interest due to its potential pharmacological properties. It can be utilized in the synthesis of various drugs and bioactive molecules. Additionally, it may have potential applications in the fields of medicine and biotechnology due to its unique chemical structure and properties.

InChI:InChI=1/C9H11NO4S/c11-9(12)6-7-10-15(13,14)8-4-2-1-3-5-8/h1-5,10H,6-7H2,(H,11,12)/p-1

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 107-95-9 3-amino propanoic acid 
• 51786-12-0 N-benzenesulfonyl-β-alanine ethyl ester 

Downstream Products

• 141956-38-9 -<1-(1H-indol-3-ylmethyl)-1-methyl-2-oxo-2-<<2-<<1-oxo-3-<(phenylsulfonyl)amino>propyl>amino>-2-phenylethyl>amino>ethyl>carbamic acid tricyclo<3.3.1.1^3,7>dec-2-yl ester 
• 154625-34-0 Pd(C₆H₅SO₂N(CH₂)2COO)(C₅H₄N)2*H₂O 
• 38378-06-2 N-(3-hydrazinyl-3-oxopropyl)benzenesulfonamide 

Relevant articles and documents

Structural and biological study of synthesized anthraquinone series of compounds with sulfonamide feature

1, 4 and 5, 8-Positions as well as type of functionalities on these positions at anthraquinone-9, 10-dione are proposed to be significant for anticancer activity. Therefore, keeping this into consideration, a series of 1-substituted anthraquinone-based compounds are designed, synthesized, characterized and biologically evaluated for anticancer activity. The structure of synthesized compounds is confirmed by spectroscopic analysis, i.e. 1D (1H and 13C) nuclear magnetic resonance (NMR), electrospray ionization-mass spectrometry (ESI-MS) studies and Fourier transform infrared (FT-IR) tools. Synthesized 1-substituted anthraquinone compounds showed cytotoxic effect against human breast cancer cell line (MCF-7), human prostate cancer cell line (PC-3) and Hela derivative human cell line (Hep 2C) (Hela derivative) cell lines. All the compounds showed mild antibacterial property in comparison to standard antibiotic streptomycin against Gram + ve and –ve bacteria. They also exhibit mild antifungal activity. In vitro calf thymus (ct)-DNA binding studies of synthesized series using UV–visible absorption spectra measurement and fluorescence tools indicate partial intercalative mode of binding. Electronic properties of synthesized analogues and mitoxantrone are compared using highest occupied molecular orbital–lowest occupied molecular orbital (HOMO–LUMO) calculation. Low energy gap between HOMO and LUMO of 1-substituted anthraquinone compounds indicates the highly charged structure of the molecules in comparison to mitoxantrone, and the same is proposed to be responsible for comparable cytotoxic activities of the synthesized 1-substituted anthraquinone molecules. Docking interaction of synthesized 1-substituted anthraquinone compounds and i-motif sequence indicates intercalative mode of binding of compounds with telomeric junction. Communicated by Ramaswamy H. Sarma.

Synthesis and structure-activity relationships of o-sulfonamido- arylhydrazides as inhibitors of LL-diaminopimelate aminotransferase (LL-DAP-AT)

Recently, ll-diaminopimelate aminotransferase (ll-DAP-AT), a pyridoxal-5′-phosphate (PLP)-dependent enzyme, was reported to catalyze a key step in the biosynthesis of l-lysine in plants and Chlamydia. Previous screening of a 29201-compound library against

PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN

The invention provides a parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/amaliorating agent that has a function such as parakeratosis inhibition, pore shrinkage, or rough skin -inhibition/abatement, poses no safety problems such as sensory irritation, and is very safe, and further provides an external composition for skin to which a compound having the above-mentioned function has been added. The parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/amaliorating agent comprises one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof. The external composition for skin comprises the one or more compounds selected from the group consisting of β-alanine derivatives and salts thereof as the above-mentioned parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/amaliorating agent.