3187-19-7 Usage
Description
2-Hydroxy-4,6-dimethoxybenzoic acid is an organic compound characterized by its unique chemical structure, featuring a hydroxyl group, two methoxy groups, and a carboxylic acid group attached to a benzene ring. This structure endows the compound with specific properties that make it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
2-Hydroxy-4,6-dimethoxybenzoic acid is used as a reagent for the synthesis of rac Zearalenone-d6, an estrogenic mycotoxin produced by Fusarium fungi commonly found in grains. 2-HYDROXY-4,6-DIMETHOXYBENZOIC ACID belongs to a group of compounds known as resorcylic acid lactones, which have potential applications in the development of pharmaceuticals targeting estrogen-related conditions.
Used in Chemical Synthesis:
2-Hydroxy-4,6-dimethoxybenzoic acid can be utilized as a key intermediate in the synthesis of various organic compounds, particularly those with potential applications in the pharmaceutical, agrochemical, and materials science industries. Its unique functional groups allow for further chemical modifications and the creation of novel molecules with specific properties and functions.
Used in Research and Development:
As a versatile organic compound, 2-Hydroxy-4,6-dimethoxybenzoic acid can be employed in research and development efforts to explore its potential applications and properties. This may include studying its interactions with other molecules, evaluating its biological activities, and investigating its potential use in the development of new drugs, materials, or chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 3187-19-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,8 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3187-19:
(6*3)+(5*1)+(4*8)+(3*7)+(2*1)+(1*9)=87
87 % 10 = 7
So 3187-19-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O5/c1-13-5-3-6(10)8(9(11)12)7(4-5)14-2/h3-4,10H,1-2H3,(H,11,12)
3187-19-7Relevant articles and documents
Regioselective ortho-carboxylation of phenols catalyzed by benzoic acid decarboxylases: A biocatalytic equivalent to the Kolbe-Schmitt reaction
Wuensch, Christiane,Gross, Johannes,Steinkellner, Georg,Lyskowski, Andrzej,Gruber, Karl,Glueck, Silvia M.,Faber, Kurt
, p. 9673 - 9679 (2014/03/21)
The enzyme catalyzed carboxylation of electron-rich phenol derivatives employing recombinant benzoic acid decarboxylases at the expense of bicarbonate as CO2 source is reported. In contrast to the classic Kolbe-Schmitt reaction, the biocatalytic equivalent proceeded in a highly regioselective fashion exclusively at the ortho-position of the phenolic directing group in up to 80% conversion. Several enzymes were identified, which displayed a remarkably broad substrate scope encompassing alkyl, alkoxy, halo and amino- functionalities. Based on the crystal structure and molecular docking simulations, a mechanistic proposal for 2,6-dihydroxybenzoic acid decarboxylase is presented.
Enantioselective synthesis of a fluorinated analogue of the orsellinic acid-type twelve-membered lactone lasiodiplodin
Runge,Haufe
, p. 8737 - 8742 (2007/10/03)
The chemoenzymatic synthesis of the racemate and the one enantiomer of the fluorinated analogue 8 of the natural cyclooxygenase inhibitor lasiodiplodin is decribed. A lipase-mediated deracemization of the fluorohydrin 18 provided the chiral, nonracemic building block for the enantioselective synthesis of the title compound. The key step was the formation of the 12-membered lactene by a ring-closing metathesis.
Macrocycle formation by ring-closing-metathesis. 2. An efficient synthesis of enantiomerically pure (R)-(+)-lasiodiplodin
Fuerstner, Alois,Kindler, Nicole
, p. 7005 - 7008 (2007/10/03)
A highly efficient and flexible route to the macrolide (R)-(+)-lasiodiplodin 1 and its de-O-methyl congener 2 is outlined, which is based on the formation of the 12-membered ring by ring-closing metathesis (RCM) as the key step.
