3187-51-7 Usage
General Description
7-Methoxy-chroman-3-carboxylic acid is a chemical compound with a molecular formula C11H10O4. It is a derivative of chroman, a ring structure found in certain natural products such as vitamin E. The compound has a methoxy group and a carboxylic acid group attached to the chroman ring. It is commonly used in organic synthesis and medicinal chemistry as a building block for creating new compounds with potential pharmaceutical properties. 7-METHOXY-CHROMAN-3-CARBOXYLIC ACID may have antioxidant and anti-inflammatory properties, and its structure makes it a valuable starting material for the synthesis of novel drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 3187-51-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,8 and 7 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3187-51:
(6*3)+(5*1)+(4*8)+(3*7)+(2*5)+(1*1)=87
87 % 10 = 7
So 3187-51-7 is a valid CAS Registry Number.
3187-51-7Relevant articles and documents
The development of benzimidazoles as selective rho kinase inhibitors
Sessions, E. Hampton,Smolinski, Michael,Wang, Bo,Frackowiak, Bozena,Chowdhury, Sarwat,Yin, Yan,Chen, Yen Ting,Ruiz, Claudia,Lin, Li,Pocas, Jennifer,Schr?ter, Thomas,Cameron, Michael D.,LoGrasso, Philip,Feng, Yangbo,Bannister, Thomas D.
scheme or table, p. 1939 - 1943 (2010/09/03)
Rho Kinase (ROCK) is a serine/threonine kinase whose inhibition could prove beneficial in numerous therapeutic areas. We have developed a promising class of ATP-competitive inhibitors based upon a benzimidazole scaffold, which show excellent potency toward ROCK (IC50 10 nM). This report details the optimization of selectivity for ROCK over other related kinases such as Protein kinase A (PKA).