31881-69-3Relevant articles and documents
Synthesis and Antioxidant Activity of N-Aminomethyl Derivatives of Ethosuximide and Pufemide Anticonvulsants
Gevorgyan, G. A.,Hakobyan, N. Z.,Hovakimyan, S. S.,Hovasyan, Z. A.,Melkonyan, A. G.,Panosyan, G. A.
, p. 385 - 389 (2020)
Abstract: Aminomethylation of 3-methyl-3-ethylpyrrolidin-2,5-dione (ethosuximide) and 3-(4-isopropoxyphenyl)pyrrolidine-2,5-dione (pufemide) with a 25% aqueous formalin solution and alkyl(aryl)amines yielded corresponding N-aminomethyl derivatives. The antioxidant activity of the synthesized compounds and their effect on some parameters of the blood coagulation system were studied.