31883-98-4Relevant articles and documents
Noyce,Evett
, p. 394 (1972)
Highly Enantioselective Construction of Hajos-Wiechert Ketone Skeletons via an Organocatalytic Vinylogous Michael/Stetter Relay Sequence
Jia, Zhi-Long,Wang, Yao,Zhao, Chuan-Gang,Zhang, Xiao-Hai,Xu, Peng-Fei
supporting information, p. 2130 - 2133 (2017/04/27)
A highly enantioselective supramolecular iminium-catalyzed vinylogous Michael addition/Stetter relay sequence has been developed. This transformation provided a series of Hajos-Wiechert-type fused bicyclic diones with three continuous stereogenic centers in good yields with excellent enantioselectivities. The obtained products can be easily transformed into other structures with potential synthetic value.
A concise, stereocontrolled total synthesis of rippertenol
Snyder, Scott A.,Wespe, Daniel A.,Von Hof, J. Marian
supporting information; experimental part, p. 8850 - 8853 (2011/08/04)
The first total synthesis of the unique terpene rippertenol, a molecule with dense stereochemical complexity arrayed on a compact framework largely devoid of functional groups, is described. Key elements include orchestrated and unique applications of aldol condensations, Diels-Alder chemistry, and a ring expansion to advance a chiral starting material containing a single chiral center into the final target in a concise and diastereocontrolled manner.
