318987-58-5

Basic information

• Product Name: ethyl 1'-benzyloxycarbonyl-7-[(6-chloro-2-naphthalenyl)sulfonyl]tetrahydro-5-oxo-spiro[8aH-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidine]-8a-carboxylate
• CAS NO: 318987-58-5
• Molecular Weight: 642.129
• Mol File: 318987-58-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 1'-benzyloxycarbonyl-7-[(6-chloro-2-naphthalenyl)sulfonyl]tetrahydro-5-oxo-spiro[8aH-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidine]-8a-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1'-benzyloxycarbonyl-7-[(6-chloro-2-naphthalenyl)sulfonyl]tetrahydro-5-oxo-spiro[8aH-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidine]-8a-carboxylate(318987-58-5)
• EPA Substance Registry System: ethyl 1'-benzyloxycarbonyl-7-[(6-chloro-2-naphthalenyl)sulfonyl]tetrahydro-5-oxo-spiro[8aH-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidine]-8a-carboxylate(318987-58-5)

Safety Data

• Hazardous Substances Data: 318987-58-5(Hazardous Substances Data)

Upstream product

• 102153-63-9 6-chloronaphth-2-ylsulfonyl chloride 
• 318987-57-4 1'-benzyloxycarbonyl-7-[(6-chloro-2-naphthalenyl)sulfonyl]tetrahydro-5-oxo-spiro[8aH-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidine]-8a-carboxylic acid 
• 1021933-34-5 C₃₁H₃₂ClN₃O₈S 
• 318986-40-2 1'-benzyloxycarbonyl-7-[(6-chloro-2-naphthalenyl)sulfonyl]tetrahydro-8a-(hydroxymethyl)-spiro[5H-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidin]-5-one 
• 318986-28-6 8a-[(acetyloxy)methyl]-7-[(6-chloro-2-naphthalenyl)sulfonyl]tetrahydro-1'-benzyl-spiro[5H-oxazolo[3,2-a]pyrazine-2(3H),4'-piperidin]-5-one 
• 318986-26-4 ethyl N-(3-acetyloxy-2-oxopropyl)-N-[(6-chloro-2-naphthalenyl)sulfonyl]glycinate 
• 318986-24-2 ethyl 2-[(6-chloronaphthalen-2-ylsulfonyl)amino]acetate 
• 64-17-5 ethanol 

Relevant articles and documents

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors IV. A series of new derivatives containing a spiro[5H-oxazolo[3,2-a]pyrazine-2(3H),4′-piperidin]-5-one skeleton

In the course of development of factor Xa (FXa) inhibitor in an investigation involving the synthesis of 1-arylsulfonyl-3-piperazinone derivatives, we found new compounds containing a unique spiro skeleton. Among such compounds, (-)-7-[(6-chloro-2-naphtha

TRICYCLIC COMPOUNDS HAVING SPIRO UNION

This invention relates to tricyclic compounds having spiro union represented by the following formula (I) or its salt which is useful as a drug, and in particular, as an inhibitor for activated blood coagulation factor X, which can be administered orally