31906-04-4

Basic information

• Product Name: Lyral
• Synonyms: 3-CYCLOHEXENE-1-CARBOXALDEHYDE, 4-(4-HYDROXY-4-METHYL PENTYL);LYRAL;HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE;4(4-hydroxy-4-methylpentyl)3-cyclohexene carboxaldehyde;Hydroxymethylpentylcyclohexenecarboxaldehyde;4-HYDROXY-4-METHYLPENTYL-3-CYCLOHEXENE-CARBOXALDEHYDE;HYDROXYMETHYLPENTYLCYCLOHEXENE-CARBOXYALDEHYDE;4-(4-Hydroxy-4-methylpentyl)cyclohex-3-encarbaldehyd
• CAS NO: 31906-04-4
• Molecular Formula: C₁₃H₂₂O₂
• Molecular Weight: 210.31
• EINECS: 250-863-4
• Product Categories: C10 to C21Organic Building Blocks;Aldehydes;Alkenes;Carbonyl Compounds;Cyclic
• Mol File: 31906-04-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 289.85°C (rough estimate)
• Flash Point: 93 °C
• Appearance: /
• Density: 0.995 g/mL at 20 °C
• Refractive Index: 1.486-1.493
• Storage Temp.: 2-8°C
• Solubility: Benzene (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 15.31±0.29(Predicted)
• CAS DataBase Reference: Lyral(CAS DataBase Reference)
• NIST Chemistry Reference: Lyral(31906-04-4)
• EPA Substance Registry System: Lyral(31906-04-4)

Safety Data

• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 2
• RTECS: GW2850000
• F: 10-23
• Hazardous Substances Data: 31906-04-4(Hazardous Substances Data)

Usage

Description

Lyral, also known as hydroxyisohexyl 3-cyclohexene carboxaldehyde, is a colorless, viscous liquid with a sweet odor reminiscent of lily of the valley. It is a mixture of isomers and is used as a fragrance ingredient in the perfumery industry. Lyral is prepared by a Diels-Alder reaction of myrcenol and acrolein in the presence of a Lewis catalyst, such as zinc chloride. It has excellent fixative properties and is known to be a suspected fragrance allergen, which may cause skin irritation in some individuals.

Uses

Used in Perfumery:
Lyral is used as a fragrance ingredient for its light floral scent and excellent fixative properties. It is particularly useful in the formulation of perfumes, colognes, and other scented products.
Used in Soap and Cosmetics:
Lyral is used as a fragrance ingredient in the soap and cosmetics industry due to its ability to enhance and prolong the scent of these products. Its fixative properties make it a valuable addition to the formulation of soaps, lotions, creams, and other personal care products.
Used in Fragrance Allergen Research:
As a suspected fragrance allergen, Lyral is also used in the research and development of products that aim to minimize the risk of skin irritation and allergic reactions in sensitive individuals. This application involves the study of its chemical properties and potential allergenic effects, as well as the development of alternative fragrance ingredients with lower allergenic potential.

Trade name

Lydocal (Hangzhou), Lyral? (IFF)

Contact allergens

Lyral ? is a synthetic blend of two isomers, and one of the most frequently encountered allergen in perfumes. It has to be listed by name in the ingredients of cosmet- ics in the EU, according to the seventh amendment of the cosmetic directive 76/768/EEC.

Upstream product

• 543-39-5 myrcenol 
• 107-02-8 acrolein 
• 40267-53-6 (E)-N,N-diethyl-3,7-dimethyl-2,6-octadienylamine 
• 68759-12-6 (E)-N,N-diethyl-7-hydroxy-3,7-octenylamine 

Downstream Products

• 67634-12-2 C₂₁H₂₉NO₃ 

Relevant articles and documents

Precursors for fragrant ketones and fragrant aldehydes

The present invention refers to fragrance precursors of formula I for a fragrant ketone of formula II and one or more fragrant aldehydes or ketones of formula III and IV, These fragrance precursors are useful in perfumery, especially in the fine and functional perfumery.