31915-94-3Relevant articles and documents
THE INFLUENCE OF (ORGANO)METALLICS "METAL-TUNING" ON STEREO- AND REGIO-CHEMICAL CONVERGENCE IN REACTIONS OF ALLYLIC CARBANIONS WITH ALDEHYDES
Yamamoto, Yoshinori,Saito, Yoshizaku,Maruyama, Kazuhiro
, p. 311 - 318 (1985)
Although the reaction of heterosubstituted allylic carbanions (2) with aldehydes generally produces a mixture of the γ- and α-adducts (4 and 3), syn-3 and anti-3 can be prepared either exclusively or predominantly by the proper choice of the organometallic compound added.
Palladium-Catalyzed Asymmetric Tandem Denitrogenative Heck/Tsuji-Trost of Benzotriazoles with 1,3-Dienes
Li, Yin-Lin,Wu, Hai-Hong,Zhang, Junliang,Zhang, Pei-Chao
supporting information, p. 13010 - 13015 (2021/09/07)
The asymmetric denitrogenative cycloaddition has emerged as a powerful tool to build chiral aza-heterocyles. However, only one example of asymmetric denitrogenative cycloaddition of benzotriazole with unsaturated hydrocarbons has been explored so far, bec
Enantioselective Addition of Pyrazoles to Dienes**
Dong, Vy M.,Jiu, Alexander Y.,Slocumb, Hannah S.,Yang, Xiao-Hui,Yeung, Charles S.
supporting information, p. 19660 - 19664 (2021/08/06)
We report the first enantioselective addition of pyrazoles to 1,3-dienes. Secondary and tertiary allylic pyrazoles can be generated with excellent regioselectivity. Mechanistic studies support a pathway distinct from previous hydroaminations: a Pd0-catalyzed ligand-to-ligand hydrogen transfer (LLHT). This hydroamination tolerates a range of functional groups and advances the field of diene hydrofunctionalization.
Cu-Catalyzed highly regioselective 1,2-hydrocarboxylation of 1,3-dienes with CO2
Zhang, Penglin,Zhou, Zhanglang,Zhang, Rumeng,Zhao, Qian,Zhang, Chun
supporting information, p. 11469 - 11472 (2020/10/12)
A practical copper-catalyzed highly regioselective 1,2-hydrocarboxylation of terminal 1,3-diene with carbon dioxide has been developed. Under mild reaction conditions, this chemistry afforded 2-benzyl-β,γ-unsaturated acid derivatives as products, which are a kind of important unit for bio-active molecules and versatile precursors for organic synthesis, with good functional group tolerance. The key intermediate in this transformation is illustrated by control experiments.