319432-22-9

Basic information

• Product Name: 7-IODO-PYRAZOLO[1,5-A]PYRIDINE
• Synonyms: 7-IODO-PYRAZOLO[1,5-A]PYRIDINE;Pyrazolo[1,5-a]pyridine, 7-iodo-;7-iodoH-pyrazolo[1,5-a]pyridine
• CAS NO: 319432-22-9
• Molecular Formula: C₇H₅IN₂
• Molecular Weight: 244.03247
• Mol File: 319432-22-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 2.01g/cm³
• Refractive Index: 1.75
• Storage Temp.: 2-8°C(protect from light)
• PKA: 1.79±0.30(Predicted)
• CAS DataBase Reference: 7-IODO-PYRAZOLO[1,5-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-IODO-PYRAZOLO[1,5-A]PYRIDINE(319432-22-9)
• EPA Substance Registry System: 7-IODO-PYRAZOLO[1,5-A]PYRIDINE(319432-22-9)

Safety Data

• Hazardous Substances Data: 319432-22-9(Hazardous Substances Data)

Usage

General Description

7-IODO-PYRAZOLO[1,5-A]PYRIDINE is a heterocyclic compound composed of a pyrazole ring fused to a pyridine ring, with an iodine atom attached to the pyrazole ring. This chemical is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and organic materials. It is known for its versatile reactivity and can undergo different chemical reactions, making it valuable in the synthesis of complex organic molecules. The presence of the iodine atom also makes it useful in certain types of organic transformations and as a reagent in various chemical processes. Additionally, 7-IODO-PYRAZOLO[1,5-A]PYRIDINE has potential applications in the development of new drugs and agrochemicals due to its unique structural features and biological activities.

InChI:InChI=1/C7H5IN2/c8-7-3-1-2-6-4-5-9-10(6)7/h1-5H

Upstream product

• 274-56-6 3-azaindolizine 
• 16205-44-0 Pyrazolo<1,5-a>pyridin-3-carbonsaeureethylester 

Downstream Products

• 319432-38-7 7-(4-Benzylpiperazin-1-yl)pyrazolo[1,5-a]pyridine 
• 319432-30-9 7-(4-Fluorophenyl)pyrazolo[1,5-a]pyridine 
• 319432-36-5 pyrazolo[1,5-a]pyridine-7-carbonitrile 
• 319432-24-1 7-Phenylpyrazolo[1,5-a]pyridine 

Relevant articles and documents

Regioselective Metalation and Functionalization of the Pyrazolo[1,5- a]pyridine Scaffold Using Mg- and Zn-TMP Bases

A regioselective functionalization of the pyrazolo[1,5-a]pyridine scaffold using Mg- and Zn-TMP bases (TMP = 2,2,6,6-tetramethylpiperidyl) in the presence or absence of BF3·OEt2 is described. Also, various functionalized pyrazolo[1,5-a]pyridines bearing an ester function (and an NHBoc or ethyl group) are magnesiated and functionalized, leading to polysubstituted heterocycles. Additionally, a sulfoxide directed ortho-metalation, followed by the transition-metal-free amination of a pyrazolo[1,5-a]pyridine sulfoxide, using a magnesium amide, is reported.