3199-69-7

Basic information

• Product Name: 2-BROMO-4-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE
• Synonyms: 2-BROMO-4-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE
• CAS NO: 3199-69-7
• Molecular Formula: C9H6BrClO
• Molecular Weight: 245.5
• Mol File: 3199-69-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-BROMO-4-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE(3199-69-7)
• EPA Substance Registry System: 2-BROMO-4-CHLORO-2,3-DIHYDRO-1H-INDEN-1-ONE(3199-69-7)

Safety Data

• Hazardous Substances Data: 3199-69-7(Hazardous Substances Data)

Upstream product

• 15115-59-0 4-chloro-2,3-dihydro-1H-inden-1-one 
• 1643-28-3 3-(2-chlorophenyl)propanoic acid 
• 52085-97-9 3-(2-chlorophenyl)propionyl chloride 
• 704-96-1 trans-2-chlorocinnamic acid 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 15115-59-0 4-chloro-2,3-dihydro-1H-inden-1-one 
• 1350748-70-7 4-chloro-1-oxo-2,3-dihydro-1H-inden-2-yl acetate 

Relevant articles and documents

Synthesis of Conformationally Locked and C-Linked Analogues of Imidazole-Based Ketene Dithioacetal Fungicides

First examples with the unknown tricyclic 4,8 b -dihydro-3 aH -indeno[1,2- d ][1,3]dithiole ring system have been prepared. Also, imidazoles linked in ring position 5 to a ketene dithioacetal and 1,3-dithiane derivatives with an exocyclic cyano- and imidazole-substituted C-C double bond are completely new. All these compounds are either conformationally locked, C-linked or six-ring analogues of the antifungal agent luliconazole. Synthesis and fungicidal activity of these sterol biosynthesis inhibitors are reported.

Synthesis and bioactivity of substituted indan-1-ylideneaminoguanidine derivatives

In our efforts to discover more potent and lasting NHE1 inhibitors, we designed and synthesized a series of substituted indan-1-ylidene aminoguanidine derivatives (5). NHE1 inhibitory activity of twenty-one compounds 5 was evaluated in a rat platelet swelling assay. It is found that most of the tested compounds possess NHE1 inhibitory effects. 2-(5-methoxybenzimidazol-2-ylthio)-5-chloro-2,3-dihydroinden-1-ylidene aminoguanidine hydrobromide (5m) proved to be sixty-nine times more potent than cariporide. Furthermore, when tested in vivo, compound 5m also displayed superior cardioprotective effects against SD rat myocardial ischemic-reperfusion injury over those of cariporide.

Derivatives of 5H, 10H-imidazo[1, 2-a]indeno[1,2-e]pyrazin-4-one, preparation thereof and medicaments containing them

Compounds having the formula (I) wherein R and R 1, similar or different, represent a hydrogen or halogen atom or a radical alkyl, alkoxy, amino, acylamino, phenylureido, --N CH--N(R 2)R 3, nitro, imidazolyl, phenyl, SO 3 H or cyano; R 2 and R 3 which may