320-16-1

Basic information

• Product Name: Benzene, 2-methoxy-1,5-dinitro-3-(trifluoromethyl)-
• CAS NO: 320-16-1
• Molecular Formula: C8H5F3N2O5
• Molecular Weight: 266.133
• Mol File: 320-16-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 2-methoxy-1,5-dinitro-3-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2-methoxy-1,5-dinitro-3-(trifluoromethyl)-(320-16-1)
• EPA Substance Registry System: Benzene, 2-methoxy-1,5-dinitro-3-(trifluoromethyl)-(320-16-1)

Safety Data

• Hazardous Substances Data: 320-16-1(Hazardous Substances Data)

Upstream product

• 88-16-4 1-chloro-2-(trifluoromethyl)benzene 
• 67-56-1 methanol 
• 392-95-0 1-chloro-2,4-dinitro-6-trifluoromethylbenzene 
• 124-41-4 sodium methylate 
• 139584-40-0 4-Methoxy-benzaldehyde O-(2,4-dinitro-6-trifluoromethyl-phenyl)-oxime 
• 139584-41-1 3-Bromo-benzaldehyde O-(2,4-dinitro-6-trifluoromethyl-phenyl)-oxime 
• 139584-38-6 Benzaldehyde O-(2,4-dinitro-6-trifluoromethyl-phenyl)-oxime 

Relevant articles and documents

Reaction of (E)-O-Arylbenzaldoximes with Sodium Methoxide in Methanol. Effect of Leaving Group upon Nitrile-Forming Transition State

Reactions of (E)-O-arylbenzaldoximes 1-3 with MeONa-MeOH have been studied kinetically.The reactions proceed via competing E2 and SNAr reactions, in which the first step is rate-determining.Although the reactions were strongly influenced by the electronic effect of the β- and O-aryl substituents, they were insensitive to the steric effect of the O-aryl group, except that the SNAr reaction was retarded by the CF3 group of 2.For eliminations from 1-3 promoted by MeONa-MeOH, the kH/kD value increased and the Hammett ρ value decreased with better leaving groups.From these results, the effect of leaving group variation upon the nitrile-forming transition state is assessed.