3202-84-4

Basic information

• Product Name: N-SALICYLOYL MORPHOLINE
• Synonyms: N-SALICYLOYL MORPHOLINE;4-(2-Hydroxybenzoyl)morpholine;4-Salicyloylmorpholine;Salicyl morpholide;(2-hydroxyphenyl)-morpholin-4-ylmethanone;(2-hydroxyphenyl)-morpholin-4-yl-methanone;(2-hydroxyphenyl)-morpholino-methanone;2-(morpholine-4-carbonyl)phenol
• CAS NO: 3202-84-4
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.22582
• Mol File: 3202-84-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 175 °C
• Boiling Point: 342.69°C (rough estimate)
• Flash Point: 193°C
• Appearance: /
• Density: 1.2424 (rough estimate)
• Vapor Pressure: 7.99E-07mmHg at 25°C
• Refractive Index: 1.4950 (estimate)
• PKA: 9.03±0.30(Predicted)
• CAS DataBase Reference: N-SALICYLOYL MORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-SALICYLOYL MORPHOLINE(3202-84-4)
• EPA Substance Registry System: N-SALICYLOYL MORPHOLINE(3202-84-4)

Safety Data

• Hazardous Substances Data: 3202-84-4(Hazardous Substances Data)

Usage

General Description

N-Salicyloyl morpholine is a chemical compound that is derived from the combination of salicylic acid and morpholine. It is a white crystalline powder that is commonly used as a corrosion inhibitor and a chelating agent in various industrial applications. N-Salicyloyl morpholine is known for its ability to form stable complexes with metal ions, thereby preventing corrosion and enhancing the performance of metal surfaces. It is also used in the production of pharmaceuticals, dyes, and rubber chemicals. Additionally, this compound has been found to exhibit antifungal and antibacterial properties, making it useful in the formulation of pesticides and disinfectants. Overall, N-Salicyloyl morpholine is a versatile chemical that plays a vital role in various industries due to its corrosion inhibiting and chelating properties.

InChI:InChI=1/C11H13NO3/c13-10-4-2-1-3-9(10)11(14)12-5-7-15-8-6-12/h1-4,13H,5-8H2

Upstream product

• 110-91-8 morpholine 
• 118-55-8 phenyl Salicylate 
• 69-72-7 salicylic acid 
• 61141-14-8 anionic phenyl salicylate 
• 69630-20-2 4-(phenyloxycarbonyl)morpholine 
• 444-30-4 2-(trifluoromethyl)phenol 
• 1468-28-6 4-benzoylmorpholine 
• 90-02-8 salicylaldehyde 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1500-18-1 4-[2-(3-dimethylamino-propoxy)-benzoyl]-morpholine 
• 1500-19-2 4-[2-(2-morpholin-4-yl-ethoxy)-benzoyl]-morpholine 
• 95004-56-1 [2-(morpholine-4-carbonyl)-phenoxy]-propyl-malonic acid diethyl ester 
• 102446-54-8 2-{2-hydroxy-3-[2-(morpholine-4-carbonyl)-phenoxy]-propoxy}-benzoic acid amide 
• 787576-33-4 C₁₃H₁₆BrNO₃ 
• 4438-01-1 2-(morpholinomethyl)phenol 

Relevant articles and documents

Rhoda-Electrocatalyzed Bimetallic C?H Oxygenation by Weak O-Coordination

Rhodium-electrocatalyzed arene C?H oxygenation by weakly O-coordinating amides and ketones have been established by bimetallic electrocatalysis. Likewise, diverse dihydrooxazinones were selectively accessed by the judicious choice of current, enabling twofold C?H functionalization. Detailed mechanistic studies by experiment, mass spectroscopy and cyclovoltammetric analysis provided support for an unprecedented electrooxidation-induced C?H activation by a bimetallic rhodium catalysis manifold.

Synthesis of functionalized carbamates and quinones via sequential oxidation of salicylaldehydes using TBHP as the oxidant

A sequential oxidative approach was designed to functionalize salicylaldehyde derivatives and provide corresponding bi-functional amide-carbamate and amide-quinone units. A combination of metal/metal free conditions and TBHP as the external oxidant provid

Synthesis of tertiary amides from anionically activated aromatic trifluoromethyl groups

Figure presented In this paper, a novel synthesis of tertiary amides from anionically activated aromatic trifluoromethyl groups is presented. Anionically activated trifluoromethyl groups react with secondary amines under aqueous conditions to afford tertiary amides. The mechanism involves initial elimination of hydrogen fluoride by an E1cB mechanism to afford an electrophilic quinone methide- or azafulvene-type intermediate that reacts with secondary amines under aqueous conditions to afford the tertiary amide in good yield (up to 99%).