32025-65-3

Basic information

• Product Name: 3-METHOXYPHENYLGLYOXAL HYDRATE
• Synonyms: 3-METHOXYPHENYLGLYOXAL HYDRATE;3-methoxyphenylglyoxal;3-METHOXYPHENYLGLYOXAL HYDRATE , DRY WT. BASIS;3-METHOXYPHENYLGLYOXAL HYDRATE, 97%, DRY WT. BASIS
• CAS NO: 32025-65-3
• Molecular Formula: C₉H₈O₃
• Molecular Weight: 182.17
• EINECS: -0
• Mol File: 32025-65-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 99-100°C
• Boiling Point: 95-98°C 0,05mm
• Flash Point: 95-98°C/0.05mm
• Appearance: /
• Density: 1.153 g/cm³
• Vapor Pressure: 0.00981mmHg at 25°C
• Refractive Index: 1.518
• BRN: 1935225
• CAS DataBase Reference: 3-METHOXYPHENYLGLYOXAL HYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXYPHENYLGLYOXAL HYDRATE(32025-65-3)
• EPA Substance Registry System: 3-METHOXYPHENYLGLYOXAL HYDRATE(32025-65-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• HazardClass: IRRITANT
• Hazardous Substances Data: 32025-65-3(Hazardous Substances Data)

Usage

General Description

3-Methoxyphenylglyoxal hydreate is a chemical compound with the molecular formula C9H10O4. It is a hydreate form of 3-methoxyphenylglyoxal, which is a yellow crystalline compound used as an intermediate in the synthesis of pharmaceuticals and organic compounds. This substance is commonly used in organic chemistry for the preparation of various heterocyclic compounds and as a reagent in chemical reactions. It is also used in the manufacturing of dyes, pigments, and other organic compounds. Additionally, 3-Methoxyphenylglyoxal hydreate is utilized in the research and development of new drugs and pharmaceuticals due to its unique chemical properties.

InChI:InChI=1/C9H8O3/c1-12-8-4-2-3-7(5-8)9(11)6-10/h2-6H,1H3

Upstream product

• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 87428-52-2 2-hydroxy-3'-methoxyacetophenone 
• 591-31-1 3-methoxy-benzaldehyde 

Downstream Products

• 72111-52-5 5-(3-methoxy-phenyl)-pyrazine-2,3-dicarbonitrile 
• 121041-16-5 3-methoxy-6-(3'-methoxybenzylthio)-2-(3''-methoxyphenyl)imidazo<1,2-b>pyridazine 
• 121247-05-0 6-chloro-3-methoxy-2-(3'-methoxyphenyl)imidazo<1,2-b>pyridazine 
• 1167571-66-5 2-chloro-3-(3-methoxyphenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine 
• 69467-02-3 5-(3-methoxyphenyl)-3-(methylthio)-1,2,4-triazine 
• 1227411-40-6 3-(1-hydroxy-2-(3-methoxyphenyl)-2-oxoethyl)-3-methylindolin-2-one 
• 1237514-13-4 acetic acid 1-(1,5-dichloro-10-oxo-9,10-dihydro-anthracen-9-yl)-2-(3-methoxy-phenyl)-2-oxo-ethyl ester 
• 1253392-55-0 6-(3-methoxyphenyl)-4-cyano-3(2H)-pyridazinone 
• 1253392-59-4 5-(3-methoxyphenyl)-4-cyano-3(2H)-pyridazinone 
• 1275575-69-3 (9H-β-carbolin-1-yl)-(3-methoxyphenyl)-methanone 
• 32345-63-4 1-(3-methoxyphenyl)-1,2-ethanediol 
• 329346-52-3 (S)-1-(m-methoxy phenyl)ethane-1,2-diol 

Relevant articles and documents

Synthesis of α-keto aldehydes via selective Cu(i)-catalyzed oxidation of α-hydroxy ketones

An efficient approach to synthesize α-keto aldehydes was established through selective oxidation of α-hydroxy ketones catalyzed by Cu(i) using oxygen as oxidant. A wide array of α-keto aldehydes was prepared with isolated yields of up to 87%. The potential utilization of this reaction was evaluated by gram-scale reactions and synthetic applications.

[1,2,4]TRIAZOLO[4,3-B][1,2,4]TRIAZINE COMPOUND, PREPARATION METHOD AND USE THEREOF

The present invention relates to a structurally novel [1,2,4]triazolo[4,3-b][1,2,4]triazine compounds represented by formula (I) or formula (II), pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates or solvates thereof, and also relates to a preparation method of the compounds, a pharmaceutical composition comprising a therapeutically effective amount of the compounds, as well as the use thereof as protein tyrosine kinase inhibitors, particularly as c-Met inhibitors, in the preparation of medicaments for the prevention and/or treatment of diseases associated with c-Met abnormality.