32041-64-8Relevant articles and documents
An azo based colorimetric probe for the detection of cysteine and lysine amino acids and its real application in human blood plasma
Razi, Syed S.,Ali, Rashid,Srivastava, Priyanka,Shahid, Mohammad,Misra, Arvind
, p. 16999 - 17007 (2014)
The present work describes the rational design and synthesis of a simple azo based colorimetric chemodosimeter to selectively detect Cys and Lys in the environment of competitive different class of amino acids in HEPES buffer under physiological conditions. The probes 3a and 3b containing aldehyde functionality upon interaction with Cys and Lys afforded stable thiazolidine and aldimine derivatives and displayed a sensitive ratiometric response in the absorption spectra due to a change in the intramolecular charge transfer (ICT) process. The whole recognition process for amino acids gives rise to a rapid significant colorimetric response with readily detectable naked-eye sensitive color changes in the real biological sample. The mechanism of interaction between the probes and amino acids has been confirmed by the optical behavior, FT-IR, NMR and ESI-MS data analysis.
Synthesis and antibacterial activities of mixed ligands complexes of Cu(II) and Zn(II) containing tridentate azo anils ligands and bidentate oxalate ion
Ameen, Muhammad,Rubina Gilini, Syeda,Naseer, Amina,Shoukat, Ishrat,Ali, Syed Danish,Sadiqa, Ayesha
, p. 3988 - 3992 (2015)
Mixed ligands complexes of copper(II) and zinc(II) were synthesized using azo anils ((HNPDBAB = 2-({2-hydroxy-5-[(4- nitrophenyl)diazenyl]benzylidene}amino)benzoic acid, HPIMNDP = 2-{[(2-hydroxyphen yl)imino]methyl}-4-[(4-nitrophenyl)diazenyl] phenol) and oxalate ion as a coordinating ligands. Elemental analysis, atomic absorption spectroscopy, FTIR, NMR, UV-visible. were used for the characterizations of synthesized azo anils ligands and their mixed ligands complexes. Distorted octahedral geometry was tentatively proposed for these new mixed ligands M(II) {Cu(II) and Zn(II)} complexes. Gram-positive (Bacillus subtilis and Staphylococcus aureus) and Gram-negative (Enterobacter aerogenes and Escherichia coli) were screen out for antibacterial activities of azo anils ligands, oxalic acid, metal salts and their mixed ligands M(II) complexes. The antibacterial activities were performed to assess the extent of inhibition potential of free ligand and their mixed ligands M(II) complexes. The results revealed that antibacterial activities of azo anils became more pronounced when these were coordinated to central metal atom.
'Naked-eye' detection of fluoride and acetate anions by using simple and efficient urea and thiourea based colorimetric sensors
Okudan, Ahmet,Erdemir, Serkan,Kocyigit, Ozcan
, p. 392 - 398 (2013)
Simple and efficient sensors 1 and 2 possessing azo and nitrophenyl as signaling units and urea and thiourea moieties as binding sites were designed and synthesized. These sensors were characterized by combination of 1H, 13C, APT, CO
Colorimetric detection and ratiometric quantification of mercury(ii) using azophenol dye: 'Dip & read' based handheld prototype device development
Singh, Gagandeep,Raj, Pushap,Singh, Harupjit,Singh, Narinder
, p. 12728 - 12738 (2018)
The extreme toxicity of mercury and its derivatives results from its high affinity for thiol groups in proteins and enzymes, leading to the dysfunction of cells and consequent health problems. Thus, developing a rapid, cheap and colorimetric sensor for detecting mercury ions at very low levels remains a challenge. Herein, we have developed a new chromogenic azophenol-based probe which allows the colorimetric detection of Hg(ii) metal ions and subsequently, showed suitability as a RGB chemodosimeter for the selective sensing of Hg(ii) in aqueous medium. The UV-vis absorption and colorimetric study showed that the azophenol-based sensor is highly selective towards Hg(ii) detection without the interference of other analytes. The color change from deep red to yellow in the complex solution after treating with mercury metal ions, which is visible by the naked-eye, makes this probe more convenient and simple to use in real sample analysis. Furthermore, for practical application of the sensor system in real time sample analysis, solid state silica based sensor chips have been developed which are impregnated with probe 1 displaying colorimetric changes for different concentrations of Hg2+, where the intensity of the red color decreased gradually towards a yellow color after the addition of Hg2+, apparently, makes them as potential candidate to conveniently monitor the concentration of Hg2+ in aqueous test solutions.
Dual detection highly selective colorimetric chemosensors for fluoride and copper(II) ions based on imine-phenol derivative
Nusuwan, Phoomirut,Jittangprasert, Piyada,Kuno, Mayuso,Pumsa-Ard, Kem,Tongraung, Pan
, p. 803 - 809 (2020)
A simple dual detection using colorimetric chemosensor, imine-phenol derivative L (bearing a 2-iminephenol group as a binding unit and a-nitrophenylazo group as a signaling unit), were synthesized for a high yield in two simple steps. Complexations of chemosensor L with various anions in acetonitrile solvent and other metal ions in DMSO/H2O solvent were monitored by UV-visible spectroscopy. The results indicated that the chemosensor L showed high selectivity for F? and Cu2+ ions. Furthermore, the complexes for L-F? and L-Cu2+ were evaluated by computational chemistry using a B3LYP/6-31G (d,p) and a B3LYP/6-311G (d,p) level of calculation. The complexes between L with F? and Cu2+ were magenta and yellow colored, respectively. Chemosensor L can be applied for the analysis of F? and Cu2+ ions with naked-eye detection making colour comparisons between the standard and the real sample. Most importantly, semi-qualitative detection of Cu2+ in water solution were successfully carried out with the developed test kit using chemosensor L.
Synthesis, spectroscopic characterization, and genotoxicity of a new group of azo-oxime metal chelates
Cabir, Beyza,Avar, Baris,Gulcan, Mehmet,Kayraldiz, Ahmet,Kurtoglu, Mukerrem
, p. 422 - 438 (2013)
A new azo-oxime ligand, 2-[(E)-(hydroxyimino)methyl]-4-[(E)-(4-nitrophenyl) diazenyl]phenol, (pxoxH2) (2), was prepared by condensation of hydroxylamminehydrochloride and 2-hydroxy5-[(4-nitrophenyl)diazenyl]benzaldehyde (1) with treatment of a solution of diazonium salt of p-nitroaniline and 2-hydroxybenzaldehyde in ethanol. The 6 coordination compounds, [Mn(pxoxH) 2 (H2 O)2 ].H2O (3), [Co(pxoxH) 2 (H2 O)2 ].4H2O (4), [Ni(pxoxH)2 (H2 O)2 ].2H2O (5), [Cu(pxoxH)2 ].H2O (6), [Zn(pxoxH)2 ].6H2O (7), and [Cd(pxoxH) 2 (H2 O)2 ].H2O (8), were prepared by reacting Mn(II), Ni(II) Cu(II), Co(II), Zn(II), and Cd(II) ions with the ligand. The structures of the compounds were elucidated from the elemental analysis data and spectroscopic studies. The azo-oxime metal complexes were also characterized by XRD, magnetic moment, molar conductivity, and thermal analyses. Elemental analyses of the chelates suggested that the metal to ligand ratio was 1:2. It was found that the ligand acts as a bidentate bending through the phenolic oxygen and nitrogen atom of the C=N-OH group similar to most oximes. Upon complexation with the ligand, the Cu(II) and Zn(II) ions formed square planar and tetrahedral structures, respectively, and the Mn(II), Ni(II), Co(II), and Cd(II) ions formed octahedral structures with 2 water molecules as axial ligands. Finally, the ligand and its complexes were assessed for their genotoxicity. TUeBITAK.
A biginelli-azophenol based robust sensor for rapid diagnosis of cyanide in real samples
Kaur, Manpreet,Kaur, Navneet,Singh, Harupjit,Singh, Narinder
, (2021/08/27)
The self-aggregation of multifunctional Biginelli-azophenol (Ligand1) in water (ONPs) led to sensitive and selective detection of toxic pollutant cyanide in an aqueous medium and solid matrix. The origin behind the excellent sensing performance of Ligand1
Triazole derived azo-azomethine dye as a new colorimetric anion chemosensor
Chatterjee, Chinmayee,Sethi, Sipun,Mukherjee, Vishwajeet,Sahu, Prabhat Kumar,Behera, Nabakrushna
, (2019/10/19)
In the pursue of developing anion sensors, an efficient triazole derived azo-azomethine dye chemosensor (S) that differentially senses F￣ and AcO￣ ions has been reported. The ions recognition ability of S was investigated by colorimetric and UV–visible spectroscopic methods. Interestingly, this chemosensor molecule is virtually inactive in presence of other anions such as Cl￣, Br￣ and I￣ and HSO4￣. We have further presented a ratiometric approach to differentiate F￣ and AcO￣ ions. The reversibility of F￣ ion binding with S was established by the addition of Ca(NO3)2 to the fluoride bound S, which led to the regeneration of S. The quantum chemical calculation of energies of unbound and bound S has been employed using Density Functional Theory (DFT) to understand the interaction between chemosensor and anions. Evidence in support of fluoride-induced deprotonation of a O–H bond during the detection of F? ion has been demonstrated by employing 1H NMR titration experiments.
