32046-62-1

Basic information

• Product Name: 5-BROMO-1H-BENZOTRIAZOLE
• Synonyms: 5-BROMO-1H-BENZOTRIAZOLE;5-BROMOBENZOTRIAZOLE;5-Bromo-1H-1,2,3-benzotriazole;5-BROMO BENZOTRIAZOLE , (5-Bromo-1H-Benzotriazole);1H-1,2,3-benzotriazole, 5-bromo-;5-bromo-1H-1,2,3-benzotriazole(SALTDATA: FREE);1H-Benzotriazole, 6-broMo-;5-Bromo-1H-benzo[d][1,2,3]triazole
• CAS NO: 32046-62-1
• Molecular Formula: C₆H₄BrN₃
• Molecular Weight: 198.02
• Mol File: 32046-62-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 340.2 °C at 760 mmHg
• Flash Point: 159.5 °C
• Appearance: /
• Density: 1.894 g/cm³
• Vapor Pressure: 8.76E-05mmHg at 25°C
• Refractive Index: 1.745
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.45±0.40(Predicted)
• CAS DataBase Reference: 5-BROMO-1H-BENZOTRIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-1H-BENZOTRIAZOLE(32046-62-1)
• EPA Substance Registry System: 5-BROMO-1H-BENZOTRIAZOLE(32046-62-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 32046-62-1(Hazardous Substances Data)

Usage

General Description

5-Bromo-1H-benzotriazole is a chemical compound with the molecular formula C6H4BrN3. It is a white to off-white crystalline powder that is commonly used in organic synthesis as a reagent and intermediate. 5-Bromo-1H-benzotriazole is often utilized as a corrosion inhibitor for copper and copper alloys, and it is also used in the manufacture of pharmaceuticals, dyes, and pigments. Additionally, it is known to be a potential mutagen and may have harmful effects on aquatic organisms, so precautions should be taken when handling and disposing of this chemical.

InChI:InChI=1/C6H4BrN3/c7-4-1-2-5-6(3-4)9-10-8-5/h1-3H,(H,8,9,10)

Upstream product

• 36615-95-9 1-acetyl-5-bromo-1H-benzotriazole 
• 1575-37-7 4-Bromo-benzene-1,2-diamine 
• 875-51-4 4-Bromo-2-nitroaniline 

Downstream Products

• 1396753-41-5 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d][1,2,3]triazole 
• 1362243-56-8 1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d][1,2,3]triazole 
• 1083181-43-4 6-bromo-1-methyl-1H-1,2,3-benzotriazole 
• 944718-31-4 5-bromo-1-methyl-1H-benzo[d][1,2,3]triazole 

Relevant articles and documents

ULTRAVIOLET-STABILIZED CORROSION INHIBITORS

According to one embodiment of the present disclosure, a method of forming an ultraviolet-stabilized corrosion inhibitor is provided. The method includes forming a functionalized azole; forming a functionalized photosensitizer; and forming an ultraviolet-stabilized corrosion inhibitor by reacting the functionalized azole with the functionalized photosensitizer. In another embodiment, an ultraviolet-stabilized corrosion inhibitor is provided. The inhibitor includes an azole bonded to a photosensitizer. In another embodiment, an article of manufacture is provided. The article of manufacture includes a material comprising a reaction product of an azole and a photosensitizer.

Does the partial molar volume of a solute reflect the free energy of hydrophobic solvation?

Halogenated heterocyclic ligands are widely used as the potent and frequently selective inhibitors of protein kinases. However, the exact contribution of the hydrophobic solvation of a free ligand is rarely accounted for the balance of interactions contributing to the free energy of ligand binding. Herein, we propose a new experimental method based on volumetric data to estimate the hydrophobicity of a ligand. We have tested this approach for a series of ten variously halogenated benzotriazoles, the binding affinity of which to the target protein kinase CK2 was assessed with the use of thermal shift assay. According to the hierarchical clustering procedure, the excess volume, defined as the difference between the experimentally determined partial molar volume and the calculated in silico molecular volume, was found to be distant from any commonly used hydrophobicity descriptors of the ligand. The excess volume, however, properly predicts solute binding affinity. On the way, we have proved that the binding of halogenated benzotriazoles to the protein kinase CK2 is driven mostly by hydrophobic interactions.

CHEMICAL-MECHANICAL POLISHING COMPOSITION COMPRISING BENZOTRIAZOLE DERIVATIVES AS CORROSION INHIBITORS

A chemical-mechanical polishing (CMP) composition is provided comprising (A) one or more compounds selected from the group of benzotriazole derivatives which act as corrosion inhibitors and (B) inorganic particles, organic particles, or a composite or mixture thereof. The invention also relates to the use of certain compounds selected from the group of benzotriazole derivatives as corrosion inhibitors, especially for increasing the selectivity of a chemical mechanical polishing (CMP) composition for the removal of tantalum or tantalum nitride from a substrate for the manufacture of a semiconductor device in the presence of copper on said substrate.