320742-78-7Relevant articles and documents
Synthesis and biological activity of kalkitoxin and its analogues
Umezawa, Taiki,Sueda, Manabu,Kamura, Takao,Kawahara, Teppei,Han, Xuerong,Okino, Tatsufumi,Matsuda, Fuyuhiko
, p. 357 - 370 (2012/02/15)
Total syntheses of kalkitoxin, isolated from the Caribbean Lyngbya majuscula, and its analogues, 3-epi-, 7-epi-, 8-epi-, 10-epi-, 10-nor-, and 16-nor-kalkitoxin, were achieved via oxazolidinone-based diastereoselective 1,4-addition reaction of a methyl group and efficient TiCl4-mediated thiazoline ring formation as the key steps. The biological activities of synthetic kalkitoxin and its analogues were evaluated with brine shrimp.
Structure, synthesis, and biological properties of kalkitoxin, a novel neurotoxin from the marine cyanobacterium Lyngbya majuscula [24]
Wu,Okino,Nogle,Marquez,Williamson,Sitachitta,Berman,Murray,McGough,Jacobs,Colsen,Asano,Yokokawa,Shioiri,Gerwick
, p. 12041 - 12042 (2007/10/03)
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